HitPredict

Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z)
Gene: PSMB7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 409 Hs			1 277
+	Hs
		656184 RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656577 RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		656690 RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Hs
		656183 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656576 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		656689 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Hs
		1303496 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		PSB7_HUMAN (1-277): 2.34e-107: 314: 100.00
+	Hs
		1303490 UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68		PSB7_HUMAN (1-277): 2.34e-107: 314: 100.00
+	Sc
		625921 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		PSB2_YEAST (11-272): 6.97e-82: 248: 54.92
+	Sc
		689162 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		PSA5_YEAST (13-253): 6.07e-77: 236: 20.62
+	Sc
		675403 RAD23_YEAST (1-407): 2.12e-72: 233: 28.41		PSB5_YEAST (5-246): 1.85e-70: 220: 22.54
+	Hs
		656337 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656660 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		656793 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Hs
		656327 UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656655 UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		656323 UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656789 UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Hs
		656783 UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Dm
		47630 Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08		A0AQH0_DROME (42-227): 1.55e-22: 94.4: 29.41