HitPredict

Interactor 1: CCNE (P54733)
G1/S-specific cyclin-E (DmCycE)
Gene: CycE

Interactor 2: RBF (Q24472)
Retinoblastoma family protein
Gene: RBF

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	0.60	0.381

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007307 - eggshell chorion gene amplification GO:0042127 - regulation of cell population proliferation
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 709 Dm			1 845
+	Hs
		414171 CCNE1_HUMAN (215-664): 1.58e-128: 389: 35.48		RB_HUMAN (3-795): 0: 701: 20.71
+	Hs
		414150 CCNB1_HUMAN (170-601): 5.98e-104: 326: 16.85		RB_HUMAN (3-795): 0: 701: 20.71
+	Hs
		414164 CCNA2_HUMAN (146-602): 8.33e-98: 310: 20.39		RB_HUMAN (3-795): 0: 701: 20.71
+	Hs
		414240 CCNA1_HUMAN (256-601): 1.44e-95: 305: 22.32		RB_HUMAN (3-795): 0: 701: 20.71
+	Hs
		624544 CCNE1_HUMAN (215-664): 1.58e-128: 389: 35.48		RBL1_HUMAN (573-789): 8.94e-83: 289: 32.00
+	Hs
		590128 CCNA2_HUMAN (146-602): 8.33e-98: 310: 20.39		RBL1_HUMAN (573-789): 8.94e-83: 289: 32.00
+	Hs
		660112 CCNA1_HUMAN (256-601): 1.44e-95: 305: 22.32		RBL1_HUMAN (573-789): 8.94e-83: 289: 32.00
+	Hs
		624579 CCNE1_HUMAN (215-664): 1.58e-128: 389: 35.48		RBL2_HUMAN (574-787): 9.33e-51: 195: 27.31
+	Hs
		331639 CCNE2_HUMAN (216-659): 2.64e-108: 336: 31.98		RBL2_HUMAN (574-787): 9.33e-51: 195: 27.31
+	Hs
		538529 CCNB1_HUMAN (170-601): 5.98e-104: 326: 16.85		RBL2_HUMAN (574-787): 9.33e-51: 195: 27.31
+	Hs
		590169 CCNA2_HUMAN (146-602): 8.33e-98: 310: 20.39		RBL2_HUMAN (574-787): 9.33e-51: 195: 27.31
+	Hs
		943777 CCNA1_HUMAN (256-601): 1.44e-95: 305: 22.32		RBL2_HUMAN (574-787): 9.33e-51: 195: 27.31