HitPredict

Interactor 1: C9J2U0 (C9J2U0)
Cyclin E variant ex7del (Cyclin E1)
Gene: CCNE1

Interactor 2: CDN1A (P38936)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
Gene: CDKN1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30833792
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	CDI~Cyclin_N
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 Hs			1 164
+	Hs
		624557 CCNE1_HUMAN (1-350): 4.14e-116: 344: 87.09		CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00
+	Hs
		624561 CCNE1_HUMAN (1-350): 4.14e-116: 344: 87.09		CDN1B_HUMAN (7-156): 2.96e-42: 141: 25.46
+	Hs
		758186 CCNA1_HUMAN (6-311): 3.68e-87: 272: 20.06		CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00
+	Hs
		303835 CCNB2_HUMAN (3-312): 1.95e-87: 270: 19.05		CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00
+	Hs
		538489 CCNB1_HUMAN (43-320): 4.54e-86: 268: 20.38		CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00
+	Hs
		331630 CCNE2_HUMAN (17-343): 6.72e-86: 266: 40.37		CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00
+	Xl
		841954 CCNE1_XENLA (2-346): 6.58e-108: 323: 53.32		Q91646_XENLA (14-161): 6.75e-45: 148: 25.47
+	Mm
		624384 CCNB1_MOUSE (7-320): 7.77e-88: 272: 17.18		CDN1A_MOUSE (1-164): 5.34e-65: 197: 76.83
+	Xl
		193814 CCNE3_XENLA (2-347): 4.5e-107: 320: 52.42		Q91646_XENLA (14-161): 6.75e-45: 148: 25.47
+	Mm
		763418 CCNA1_MOUSE (6-311): 2.35e-86: 268: 19.78		CDN1A_MOUSE (1-164): 5.34e-65: 197: 76.83
+	Mm
		803843 CCNE1_MOUSE (1-348): 4.17e-107: 321: 68.78		CDN1B_MOUSE (7-156): 1.74e-39: 134: 27.27
+	Xl
		841953 CCNE1_XENLA (2-346): 6.58e-108: 323: 53.32		Q5V9L9_XENLA (14-156): 1.37e-32: 114: 35.17
+	Hs
		804103 CCNA1_HUMAN (6-311): 3.68e-87: 272: 20.06		CDN1B_HUMAN (7-156): 2.96e-42: 141: 25.46
+	Xl
		1146034 Q66J45_XENLA (12-309): 1.62e-84: 263: 20.59		Q91646_XENLA (14-161): 6.75e-45: 148: 25.47
+	Hs
		303836 CCNB2_HUMAN (3-312): 1.95e-87: 270: 19.05		CDN1B_HUMAN (7-156): 2.96e-42: 141: 25.46
+	Hs
		538492 CCNB1_HUMAN (43-320): 4.54e-86: 268: 20.38		CDN1B_HUMAN (7-156): 2.96e-42: 141: 25.46
+	Hs
		331632 CCNE2_HUMAN (17-343): 6.72e-86: 266: 40.37		CDN1B_HUMAN (7-156): 2.96e-42: 141: 25.46
+	Hs
		303838 CCNB2_HUMAN (3-312): 1.95e-87: 270: 19.05		CDN1C_HUMAN (8-134): 7.02e-34: 123: 27.91
+	Hs
		538496 CCNB1_HUMAN (43-320): 4.54e-86: 268: 20.38		CDN1C_HUMAN (8-134): 7.02e-34: 123: 27.91
+	Hs
		331633 CCNE2_HUMAN (17-343): 6.72e-86: 266: 40.37		CDN1C_HUMAN (8-134): 7.02e-34: 123: 27.91