Interactor 1: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4
Interactor 2: NGEF (Q8N5V2)
Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor)
Gene: NGEF
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11336673 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | RhoGEF~fn3, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_1 |
Common GO terms | GO:0043087 - regulation of GTPase activity GO:0048013 - ephrin receptor signaling pathway |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
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Last updated: 15 Jul 2024