Protein: SEM3B
Semaphorin-3B (Sema A(V)) (Semaphorin-V) (Sema V)

Gene: SEM3B, SEMA3B
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q13214

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0005576 - extracellular region
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0007267 - cell-cell signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

154819

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.691

High

593354

PGFRA
Platelet-derived growth factor receptor alpha

1

8

High-throughput

0.691

High

841541

I12R1
Interleukin-12 receptor subunit beta-1

1

3

High-throughput

0.691

High

1057094

FMOD
Fibromodulin

1

1

High-throughput

0.691

High

1098312

EPHA7
Ephrin type-A receptor 7

1

5

High-throughput

0.691

High

1098331

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.691

High

1098339

BTNL2
Butyrophilin-like protein 2

1

4

High-throughput

0.691

High

1098328

PGCB
Brevican core protein

1

0

High-throughput

0.656

High

85978

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

6

High-throughput

0.618

High

1098325

CA054
Uncharacterized protein C1orf54

2

5

High-throughput

0.601

High

1098334

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

399440

TRGV3
T cell receptor gamma variable 3

1

1

High-throughput

0.575

High

70193

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

269189

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.553

High

685843

KRA59
Keratin-associated protein 5-9

2

6

High-throughput

0.553

High

948314

KR122
Keratin-associated protein 12-2

2

3

High-throughput

0.553

High

950467

KR108
Keratin-associated protein 10-8

2

5

High-throughput

0.553

High

950756

KR109
Keratin-associated protein 10-9

2

5

High-throughput

0.553

High

1059629

KRA11
Keratin-associated protein 1-1

2

5

High-throughput

0.553

High

1098313

PCH2
Pachytene checkpoint protein 2 homolog

2

2

High-throughput

0.553

High

1098318

RBPS2
RNA-binding protein with multiple splicing 2

2

1

High-throughput

0.553

High

1098330

CAR10
Caspase recruitment domain-containing protein 10

2

7

High-throughput

0.553

High

1098319

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.553

High

298849

LYZL6
Lysozyme-like protein 6

1

1

High-throughput

0.536

High

342549

LY86
Lymphocyte antigen 86

1

3

High-throughput

0.536

High

426080

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.536

High

488309

PPBI
Intestinal-type alkaline phosphatase

1

1

High-throughput

0.536

High

506843

CFC1
Cryptic protein

1

3

High-throughput

0.536

High

535008

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

561355

TDGF1
Protein Cripto

1

3

High-throughput

0.536

High

567846

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.536

High

570665

EDN3
Endothelin-3

1

1

High-throughput

0.536

High

582327

ARSA
Arylsulfatase A

1

1

High-throughput

0.536

High

657555

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.536

High

880003

DNSL1
Deoxyribonuclease-1-like 1

1

2

High-throughput

0.536

High

933173

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

3

High-throughput

0.536

High

935726

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.536

High

1030157

IL5RA
Interleukin-5 receptor subunit alpha

1

3

High-throughput

0.536

High

1098310

PTC1
Protein patched homolog 1

1

8

High-throughput

0.536

High

1098321

TMM25
Transmembrane protein 25

1

2

High-throughput

0.536

High

1098327

GGH
Gamma-glutamyl hydrolase

1

1

High-throughput

0.536

High

1098332

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.536

High

1098335

CBLN4
Cerebellin-4

1

6

High-throughput

0.536

High

1098337

DNJB9
DnaJ homolog subfamily B member 9

1

5

High-throughput

0.536

High

1098340

CLC11
C-type lectin domain family 11 member A

1

5

High-throughput

0.536

High

517000

NT2NC
Notch homolog 2 N-terminal-like protein C

1

10

High-throughput

0.515

High

133500

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

635424

C4BPB
C4b-binding protein beta chain

1

0

High-throughput

0.513

High

1098315

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.513

High

1098324

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.513

High

1098333

PAK6
Serine/threonine-protein kinase PAK 6

1

1

High-throughput

0.494

High

224480

PI15
Peptidase inhibitor 15

1

2

High-throughput

0.489

High

449601

KLK1
Kallikrein-1

1

10

High-throughput

0.489

High

597797

CRIS2
Cysteine-rich secretory protein 2

1

2

High-throughput

0.489

High

1098323

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

5

High-throughput

0.489

High

1098320

NT2NA
Notch homolog 2 N-terminal-like protein A

1

10

High-throughput

0.481

High

218138

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

396032

ESR1
Estrogen receptor

1

4

High-throughput

0.479

High

976802

LCN6
Epididymal-specific lipocalin-6

1

3

High-throughput

0.445

High

1047532

NOTC2
Neurogenic locus notch homolog protein 2

1

4

High-throughput

0.445

High

514

NBPFJ
NBPF family member NBPF19

1

4

High-throughput

0.439

High

613021

EGR1
Early growth response protein 1

1

1

High-throughput

0.437

High

872287

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.437

High

1098311

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

833622

NAA10
N-alpha-acetyltransferase 10

2

0

High-throughput

0.316

High

1098316

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.316

High

1098317

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

1098322

BOLL
Protein boule-like

2

0

High-throughput

0.316

High

1098329

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

907408

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.279

Low

1034725

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1098314

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

1098336

UQCC1
Ubiquinol-cytochrome c reductase complex assembly factor 1

1

0

High-throughput

0.279

Low

1098326

CBP
CREB-binding protein

1

0

Small-scale

0.251

Low

1098338

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

239051

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025