Protein: CASL
Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55]

Gene: CASL, NEDD9
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q14511

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0001772 - immunological synapse
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

275570

BCAR3
Breast cancer anti-estrogen resistance protein 3

4

20

Small-scale

0.910

High

802843

CRKL
Crk-like protein

4

20

Small-scale

0.893

High

639746

IKBA
NF-kappa-B inhibitor alpha

3

14

High-throughput

0.871

High

802600

CRK
Adapter molecule crk

3

20

Small-scale

0.857

High

1054763

CASL
Enhancer of filamentation 1

2

12

Small-scale

0.807

High

882295

BCAR1
Breast cancer anti-estrogen resistance protein 1

2

16

Small-scale

0.789

High

337474

ABL1
Tyrosine-protein kinase ABL1

2

20

Small-scale

0.754

High

433761

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.724

High

983614

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.713

High

950182

SMAD3
Mothers against decapentaplegic homolog 3

4

5

Small-scale

0.703

High

1054793

DOCK9
Dedicator of cytokinesis protein 9

1

4

High-throughput

0.698

High

1054783

BANP
Protein BANP

5

0

High-throughput

0.689

High

1054767

TRIP6
Thyroid receptor-interacting protein 6

3

14

Small-scale

0.674

High

1054768

NAB2
NGFI-A-binding protein 2

4

0

High-throughput

0.673

High

1054780

DOCK3
Dedicator of cytokinesis protein 3

1

7

Small-scale

0.665

High

1054800

NOTC3
Neurogenic locus notch homolog protein 3

1

4

Small-scale

0.647

High

1054779

RFX6
DNA-binding protein RFX6

3

0

High-throughput

0.646

High

1054799

FZR1
Fizzy-related protein homolog

2

6

Small-scale

0.629

High

1054766

RHEB
GTP-binding protein Rheb

2

8

High-throughput

0.628

High

981578

REL
Proto-oncogene c-Rel

2

4

High-throughput

0.628

High

1054787

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.623

High

1054786

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

15

High-throughput

0.621

High

411721

LCK
Tyrosine-protein kinase Lck

1

20

Small-scale

0.618

High

412193

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

1047047

RPGF1
Rap guanine nucleotide exchange factor 1

1

3

Small-scale

0.618

High

1052197

SRC8
Src substrate cortactin

1

20

Small-scale

0.618

High

1052824

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.618

High

1054782

SH2D3
SH2 domain-containing protein 3C

1

20

Small-scale

0.618

High

536830

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.613

High

150126

BORG1
Cdc42 effector protein 2

2

1

High-throughput

0.606

High

241220

TBX19
T-box transcription factor TBX19

2

2

High-throughput

0.606

High

734627

TRI23
E3 ubiquitin-protein ligase TRIM23

2

4

High-throughput

0.606

High

829848

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.606

High

862619

FOSB
Protein FosB

2

6

High-throughput

0.606

High

1020659

TRAF2
TNF receptor-associated factor 2

2

2

High-throughput

0.606

High

1054764

K1H2
Keratin, type I cuticular Ha2

2

2

High-throughput

0.606

High

1054774

EEIG1
Early estrogen-induced gene 1 protein

2

1

High-throughput

0.606

High

1054775

LHX8
LIM/homeobox protein Lhx8

2

14

High-throughput

0.606

High

1054777

DPPA4
Developmental pluripotency-associated protein 4

2

1

High-throughput

0.606

High

1054785

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.606

High

1054788

EXOS8
Exosome complex component RRP43

2

1

High-throughput

0.606

High

1054791

PRAM
PML-RARA-regulated adapter molecule 1

2

12

High-throughput

0.606

High

1054796

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.606

High

1054770

SMAD1
Mothers against decapentaplegic homolog 1

2

5

Small-scale

0.600

High

1054789

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

5

Small-scale

0.586

High

48663

MED19
Mediator of RNA polymerase II transcription subunit 19

2

0

High-throughput

0.580

High

49951

F168B
Myelin-associated neurite-outgrowth inhibitor

2

0

High-throughput

0.580

High

735052

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.580

High

1012232

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1054773

ACTMP
Actin maturation protease

2

0

High-throughput

0.580

High

557691

NCK1
SH2/SH3 adapter protein NCK1

1

20

Small-scale

0.561

High

985955

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

3

Small-scale

0.561

High

1054784

MICA1
[F-actin]-monooxygenase MICAL1

1

8

Small-scale

0.561

High

970570

ID2
DNA-binding protein inhibitor ID-2

1

3

Small-scale

0.552

High

310942

SNAPN
SNARE-associated protein Snapin

1

2

High-throughput

0.541

High

299516

KLH18
Kelch-like protein 18

1

3

High-throughput

0.536

High

1054798

TINAG
Tubulointerstitial nephritis antigen

1

2

High-throughput

0.536

High

1054772

Q49AR9
ANKS1A protein

1

11

High-throughput

0.515

High

1054781

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.513

High

1016770

TFCP2
Alpha-globin transcription factor CP2

1

4

High-throughput

0.508

High

160564

AURKA
Aurora kinase A

1

3

Small-scale

0.501

High

394717

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

861753

PLK1
Serine/threonine-protein kinase PLK1

1

5

Small-scale

0.501

High

983485

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

8

Small-scale

0.501

High

787233

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.486

High

1054790

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.486

High

515

NBPFJ
Neuroblastoma breakpoint family member 19

1

2

High-throughput

0.481

High

1054771

ZYX
Zyxin

1

15

Small-scale

0.481

High

1054778

NT2NA
Notch homolog 2 N-terminal-like protein A

1

4

High-throughput

0.481

High

1054801

KLH20
Kelch-like protein 20

1

3

High-throughput

0.481

High

262004

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.480

High

396589

ITB3
Integrin beta-3

1

2

Small-scale

0.479

High

443518

VIME
Vimentin

1

6

Small-scale

0.479

High

724828

MYH9
Myosin-9

1

5

Small-scale

0.479

High

823395

PAXI
Paxillin

1

11

Small-scale

0.479

High

1054765

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1054769

SMAD2
Mothers against decapentaplegic homolog 2

1

5

Small-scale

0.479

High

1054776

CSPG4
Chondroitin sulfate proteoglycan 4

1

5

Small-scale

0.479

High

1054795

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

5

Small-scale

0.479

High

484604

NT2NC
Notch homolog 2 N-terminal-like protein C

1

5

High-throughput

0.470

High

952987

PR20C
Proline-rich protein 20C

1

1

High-throughput

0.470

High

1054792

Q9BS75
KLHL20 protein

1

4

High-throughput

0.470

High

551523

TFE2
Transcription factor E2-alpha

1

0

Small-scale

0.460

High

1054794

SAV1
Protein salvador homolog 1

1

7

Small-scale

0.457

High

1054797

TBK1
Serine/threonine-protein kinase TBK1

1

7

Small-scale

0.445

High

953075

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024