HitPredict

Interactor 1: PRS6B (P54775)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (CIP21) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: Psmc4

Interactor 2: SPAST (Q9QYY8)
Spastin (EC 5.6.1.1)
Gene: SPAST

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~AAA, AAA~AAA_lid_3, AAA~Vps4_C, AAA_lid_3~AAA_lid_3, AAA_lid_3~Vps4_C, AAA~Prot_ATP_ID_OB
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 418 Mm			1 614
+	At
		1352074 PRS4A_ARATH (8-412): 2.3e-137: 402: 47.43		PS10A_ARATH (196-610): 3.94e-114: 348: 25.18
+	At
		1341457 PRS4A_ARATH (8-412): 2.3e-137: 402: 47.43		PS10B_ARATH (203-610): 9.45e-113: 344: 25.12
+	Af
		191422 PAN_ARCFU (44-409): 5.51e-120: 356: 50.82		PAN_ARCFU (277-596): 3.32e-113: 345: 32.82
+	Hs
		798714 PRS6B_HUMAN (1-418): 1.55e-138: 404: 99.76		AFG2A_HUMAN (16-235): 7.69e-45: 173: 10.61
+	Hs
		87548 PRS6B_HUMAN (1-418): 1.55e-138: 404: 99.76		C9JUP7_HUMAN (1-344): 4.57e-45: 173: 9.46
+	Hs
		798623 PRS6B_HUMAN (1-418): 1.55e-138: 404: 99.76		TERA_HUMAN (1-344): 8.28e-45: 172: 9.46
+	At
		870963 PRS4A_ARATH (8-412): 2.3e-137: 402: 47.43		CD48A_ARATH (11-284): 2.81e-43: 168: 9.54
+	Hs
		907100 PRS8_HUMAN (38-418): 7.14e-121: 358: 42.26		AFG2A_HUMAN (16-235): 7.69e-45: 173: 10.61
+	Hs
		874773 PRS8_HUMAN (38-418): 7.14e-121: 358: 42.26		TERA_HUMAN (1-344): 8.28e-45: 172: 9.46
+	Dm
		820486 PRS4_DROME (7-412): 1.92e-118: 353: 45.59		TERA_DROME (1-302): 1.72e-45: 174: 10.37
+	Hs
		874772 PRS4_HUMAN (32-412): 6.68e-119: 355: 48.83		TERA_HUMAN (1-344): 8.28e-45: 172: 9.46