HitPredict

Interactor 1: PP1B (P48462)
Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing)
Gene: flw

Interactor 2: Q8SWT8 (Q8SWT8)
Protein phosphatase 1 regulatory subunit
Gene: Gbs-70E

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	24727027
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	CBM_21~Metallophos
Common GO terms	GO:0000164 - protein phosphatase type 1 complex GO:0005979 - regulation of glycogen biosynthetic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Dm			1 330
+	Dm
		873531 PP11_DROME (1-330): 0: 563: 81.21		Q8SWT8_DROME (1-330): 1.57e-159: 450: 100.00
+	Ce
		115256 GLC7B_CAEEL (1-328): 0: 582: 82.37		H2KYT5_CAEEL (21-330): 8.14e-109: 323: 32.21
+	Ce
		876759 GLC7B_CAEEL (1-328): 0: 582: 82.37		Q400N3_CAEEL (21-330): 3.21e-108: 321: 32.21
+	Hs
		968363 PP1B_HUMAN (1-329): 0: 581: 88.75		PPR3B_HUMAN (54-297): 7.53e-89: 269: 32.16
+	Hs
		968490 PP1B_HUMAN (1-329): 0: 581: 88.75		PPR3C_HUMAN (81-305): 1.75e-86: 264: 32.91
+	Hs
		786706 PP1G_HUMAN (1-330): 0: 572: 82.48		PPR3B_HUMAN (54-297): 7.53e-89: 269: 32.16
+	Hs
		967834 PP1A_HUMAN (1-326): 0: 570: 82.73		PPR3B_HUMAN (54-297): 7.53e-89: 269: 32.16
+	Hs
		786939 PP1G_HUMAN (1-330): 0: 572: 82.48		PPR3C_HUMAN (81-305): 1.75e-86: 264: 32.91
+	Hs
		968041 PP1A_HUMAN (1-326): 0: 570: 82.73		PPR3C_HUMAN (81-305): 1.75e-86: 264: 32.91
+	Hs
		968321 PP1B_HUMAN (1-329): 0: 581: 88.75		PPR3A_HUMAN (52-314): 1.36e-71: 242: 24.72
+	Hs
		786632 PP1G_HUMAN (1-330): 0: 572: 82.48		PPR3A_HUMAN (52-314): 1.36e-71: 242: 24.72
+	Hs
		967766 PP1A_HUMAN (1-326): 0: 570: 82.73		PPR3A_HUMAN (52-314): 1.36e-71: 242: 24.72
+	Mm
		968192 PP1A_MOUSE (1-326): 0: 570: 82.42		PPR3A_MOUSE (52-317): 3.11e-71: 240: 24.45
+	Dm
		873638 PP1B_DROME (1-330): 0: 592: 100.00		GBS76_DROME (45-280): 7.59e-59: 202: 23.65
+	Hs
		342074 PP1G_HUMAN (1-330): 0: 572: 82.48		PPR3D_HUMAN (66-282): 5.61e-67: 213: 25.00
+	Hs
		342077 PP1A_HUMAN (1-326): 0: 570: 82.73		PPR3D_HUMAN (66-282): 5.61e-67: 213: 25.00
+	Mm
		59421 PP1A_MOUSE (1-326): 0: 570: 82.42		A2AJW4_MOUSE (40-282): 8.4e-67: 212: 25.00
+	Hs
		85418 PP1A_HUMAN (1-326): 0: 570: 82.73		PP13G_HUMAN (42-285): 2.33e-57: 191: 22.26
+	Hs
		967976 PP1A_HUMAN (1-326): 0: 570: 82.73		PPR3E_HUMAN (103-293): 1.81e-55: 183: 26.02
+	Hs
		786687 PP1G_HUMAN (1-330): 0: 572: 82.48		PPR3F_HUMAN (86-309): 4.79e-41: 154: 16.82