HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (EC 3.6.1.-) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.964

The method score is based on:

Property Details
Experiments 33961781, 35271311, 37071682, 36652389, 28524877, 31839598, 24981860, 35235311
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0005524 - ATP binding
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
GO:0005874 - microtubule
and 12 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 541
Hs

1 539
+ Hs
+ Hs
+ Bt
+ Hs
+ Bt
+ Sc
+ Dm
+ Mm
+ Dm
+ Dm
+ Hs
+ Ph
+ Hs
+ Sc
+ Sc
+ Bt

Service provided by Combinatics, Japan

Last updated: 11Aug2025