HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	23383273, 37776851
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 806
+	Hs
		881843 TCPG_HUMAN (14-540): 0: 574: 33.15		TERA_HUMAN (1-806): 0: 774: 100.00
+	Hs
		935053 TCPH_HUMAN (12-539): 0: 572: 29.64		TERA_HUMAN (1-806): 0: 774: 100.00
+	Dm
		1267243 Q7KKI0_DROME (5-533): 0: 584: 71.46		TERA_DROME (5-806): 0: 760: 83.09
+	Dm
		1267948 Q9VHL2_DROME (14-541): 0: 580: 28.14		TERA_DROME (5-806): 0: 760: 83.09
+	Sc
		679761 TCPE_YEAST (3-540): 0: 583: 59.89		CDC48_YEAST (2-806): 0: 740: 67.75
+	Hs
		610588 TCPA_HUMAN (26-541): 0: 548: 32.08		TERA_HUMAN (1-806): 0: 774: 100.00
+	Sc
		679805 TCPH_YEAST (7-540): 0: 544: 30.30		CDC48_YEAST (2-806): 0: 740: 67.75
+	Sc
		679686 TCPG_YEAST (12-541): 0: 542: 31.98		CDC48_YEAST (2-806): 0: 740: 67.75
+	Hs
		899312 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		TERA_HUMAN (1-806): 0: 774: 100.00
+	Sc
		679687 TCPD_YEAST (32-533): 2.32e-99: 312: 36.89		CDC48_YEAST (2-806): 0: 740: 67.75