HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: PHLP (Q13371)
Phosducin-like protein (PHLP)
Gene: PDCL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

Property	Details
Experiments	33961781, 35271311, 15889144, unassigned3799
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~Phosducin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 301
+	Hs
		881905 TCPG_HUMAN (14-540): 0: 574: 33.15		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		1103651 TCPH_HUMAN (12-539): 0: 572: 29.64		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		876167 TCPE_HUMAN (1-541): 0: 637: 100.00		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		155737 TCPE_HUMAN (1-541): 0: 637: 100.00		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85
+	Hs
		882156 TCPG_HUMAN (14-540): 0: 574: 33.15		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		1407567 TCPH_HUMAN (12-539): 0: 572: 29.64		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Dm
		1321053 Q9VHL2_DROME (14-541): 0: 580: 28.14		PHLP2_DROME (73-299): 3.02e-62: 198: 22.79
+	Hs
		610886 TCPA_HUMAN (26-541): 0: 548: 32.08		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		155739 TCPG_HUMAN (14-540): 0: 574: 33.15		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85
+	Hs
		155798 TCPH_HUMAN (12-539): 0: 572: 29.64		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85
+	Sc
		823645 TCPE_YEAST (3-540): 0: 583: 59.89		PLP1_YEAST (97-301): 2.52e-45: 154: 20.36
+	Sc
		823660 TCPE_YEAST (3-540): 0: 583: 59.89		PLP2_YEAST (71-301): 1.51e-43: 152: 15.66
+	Hs
		155728 TCPA_HUMAN (26-541): 0: 548: 32.08		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85
+	Sc
		844438 TCPH_YEAST (7-540): 0: 544: 30.30		PLP1_YEAST (97-301): 2.52e-45: 154: 20.36
+	Sc
		810887 TCPG_YEAST (12-541): 0: 542: 31.98		PLP1_YEAST (97-301): 2.52e-45: 154: 20.36
+	Sc
		844453 TCPH_YEAST (7-540): 0: 544: 30.30		PLP2_YEAST (71-301): 1.51e-43: 152: 15.66
+	Sc
		810919 TCPG_YEAST (12-541): 0: 542: 31.98		PLP2_YEAST (71-301): 1.51e-43: 152: 15.66
+	Hs
		899372 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00
+	Hs
		899579 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		PDCL3_HUMAN (74-301): 5.7e-67: 210: 26.78
+	Hs
		155741 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		TXND9_HUMAN (104-287): 1.43e-50: 168: 18.85