HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: CXAR (P78310)
Coxsackievirus and adenovirus receptor (CAR) (hCAR) (CVB3-binding protein) (Coxsackievirus B-adenovirus receptor) (HCVADR)
Gene: CXADR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005912 - adherens junction GO:0030054 - cell junction and 1 others more... GO:0050839 - cell adhesion molecule binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 365
+	Rn
		193557 AFAD_RAT (1-1824): 0: 1220: 92.63		JAM1_RAT (3-305): 6.26e-50: 171: 20.00
+	Hs
		876552 AFAD_HUMAN (1-1824): 0: 1279: 100.00		JAM1_HUMAN (148-320): 1.14e-13: 72.7: 15.35
+	Hs
		876457 AFAD_HUMAN (1-1824): 0: 1279: 100.00		TITIN_HUMAN (10-144): 8.96e-09: 59.6: 15.56
+	Hs
		940425 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		1066534 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		VSIG2_HUMAN (4-321): 2.33e-57: 191: 27.30
+	Hs
		940575 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		1066503 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		ESAM_HUMAN (3-365): 4.67e-54: 184: 23.59
+	Hs
		1066699 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		CLMP_HUMAN (29-361): 3.23e-53: 182: 31.05
+	Hs
		1066319 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		NEGR1_HUMAN (27-318): 5.18e-44: 157: 16.56
+	Hs
		940421 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		940598 NEB1_HUMAN (1002-1092): 1.04e-19: 98.7: 40.00		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		940410 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		940491 LNX2_HUMAN (908-1089): 8.99e-18: 91.8: 18.13		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Mm
		956922 LNX2_MOUSE (973-1126): 6.83e-17: 88.9: 20.38		CXAR_MOUSE (1-365): 2.86e-81: 254: 89.86
+	Mm
		936319 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		DCC_MOUSE (1-365): 1.86e-36: 142: 12.88
+	Rn
		1337448 PARD3_RAT (937-1811): 3.83e-18: 93.7: 12.90		JAM1_RAT (3-305): 6.26e-50: 171: 20.00
+	Hs
		1077864 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		MYLK_HUMAN (128-230): 1.27e-15: 80.7: 17.93
+	Mm
		1143386 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		NRCAM_MOUSE (1-365): 1.19e-26: 113: 11.98
+	Dm
		113559 M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95		Q9VQ08_DROME (11-335): 1.41e-23: 104: 10.54
+	Hs
		1050029 SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85		LRIG1_HUMAN (18-136): 4.76e-10: 63: 16.81