HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: VANG2 (Q9ULK5)
Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2)
Gene: VANGL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 521
+	Hs
		876447 AFAD_HUMAN (1-1824): 0: 1279: 100.00		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Mm
		1143382 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		VANG1_MOUSE (21-521): 0: 765: 71.60
+	Hs
		883931 SYJ2B_HUMAN (1013-1098): 2.51e-20: 91: 32.96		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Mm
		1143470 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		VANG2_MOUSE (1-521): 0: 724: 99.42
+	Rn
		677774 DLG4_RAT (1002-1238): 9.23e-28: 123: 17.51		VANG2_RAT (1-521): 0: 724: 99.42
+	Mm
		1193536 SCRIB_MOUSE (989-1138): 1.02e-21: 105: 25.33		VANG2_MOUSE (1-521): 0: 724: 99.42
+	Hs
		883951 SYJ2B_HUMAN (1013-1098): 2.51e-20: 91: 32.96		VANG2_HUMAN (1-521): 0: 725: 100.00