HitPredict

Interactor 1: BRPF1 (P55201)
Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)
Gene: BRPF1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25281266
Identification Methods	x-ray crystallography, isothermal titration calorimetry
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1214 Hs			1 103
+	Hs
		917442 JADE1_HUMAN (74-656): 7.35e-135: 434: 25.83		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917675 JADE3_HUMAN (73-656): 1.19e-118: 389: 25.21		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356792 NTO1_YEAST (119-698): 3.26e-123: 399: 25.45		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		301132 KDM4B_HUMAN (86-464): 9e-76: 275: 22.72		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917657 PHIP_HUMAN (425-1054): 9.63e-64: 240: 13.84		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		600119 TAF1_HUMAN (382-1054): 4.35e-62: 235: 15.61		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917576 TAF1L_HUMAN (382-945): 1.49e-57: 221: 14.29		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		299043 PHF14_HUMAN (241-603): 4.93e-57: 216: 21.69		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917979 BRD7_HUMAN (574-748): 2.04e-56: 210: 32.77		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		256958 KDM4A_HUMAN (283-488): 9.15e-52: 201: 33.33		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356607 SNT2_YEAST (276-466): 7.64e-46: 183: 22.94		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Mm
		918262 BRDT_MOUSE (615-873): 9.03e-38: 156: 19.16		H4_MOUSE (1-103): 1.38e-48: 151: 100.00