HitPredict

Interactor 1: CDN2D (P55273)
Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)
Gene: CDKN2D

Interactor 2: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	27107012
Identification Methods	two hybrid, barcode fusion genetics two hybrid, split luciferase complementation, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 440
+	Hs
		1032657 RAI14_HUMAN (5-142): 1.32e-35: 132: 25.18		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		1032620 EHMT1_HUMAN (2-120): 2.72e-26: 105: 20.83		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		881299 EHMT1_HUMAN (2-120): 2.72e-26: 105: 20.83		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		790724 CDN2A_HUMAN (8-130): 3.41e-23: 91.3: 49.19		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		883502 RIPK4_HUMAN (7-104): 5.7e-18: 81.7: 28.00		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		1032610 Q9H4D1_HUMAN (7-104): 9.6e-18: 81.3: 28.00		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		1032558 EHMT2_HUMAN (2-77): 4.8e-14: 70.7: 15.60		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		57010 A2ABF8_HUMAN (2-77): 4.95e-14: 70.4: 15.60		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		881258 EHMT2_HUMAN (2-77): 4.8e-14: 70.7: 15.60		CTBP2_HUMAN (10-439): 0: 538: 80.23