HitPredict

Interactor 1: FOXG1 (P55316)
Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3)
Gene: FOXG1

Interactor 2: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11387330
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 489 Hs			1 465
+	Hs
		206841 FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70		SMAD1_HUMAN (1-465): 0: 658: 100.00
+	Hs
		950157 FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90		SMAD3_HUMAN (3-465): 0: 556: 59.66
+	Hs
		206824 FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70		SMAD3_HUMAN (3-465): 0: 556: 59.66
+	Hs
		877694 FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84		SMAD3_HUMAN (3-465): 0: 556: 59.66
+	Hs
		885155 FOXL2_HUMAN (131-270): 1.05e-47: 170: 48.57		SMAD3_HUMAN (3-465): 0: 556: 59.66
+	Hs
		1016166 FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90		SMAD4_HUMAN (13-454): 1.6e-150: 441: 34.28
+	Hs
		206837 FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70		SMAD4_HUMAN (13-454): 1.6e-150: 441: 34.28