HitPredict

Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30737378
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 488
+	Hs
		1270358 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1270370 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		903404 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		282986 CIAO1_HUMAN (12-93): 1.73e-09: 60: 28.09		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		903202 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Dm
		1182201 EBI_DROME (206-320): 5.33e-18: 86.4: 24.19		Q7KTS4_DROME (10-430): 0: 560: 57.11
+	Dm
		1279322 EBI_DROME (206-320): 5.33e-18: 86.4: 24.19		Q9VNC2_DROME (10-430): 0: 556: 56.88
+	Hs
		177249 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		1157816 SEC13_MOUSE (156-317): 3.48e-25: 104: 23.78		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Hs
		1260173 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37