Protein: TRPM7
Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) [Cleaved into: TRPM7 kinase, cleaved form (M7CK); TRPM7 channel, cleaved form]

Gene: TRPM7
Organism: Homo sapiens
Interactions: 130
UniProt ID: Q96QT4

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0003779 - actin binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005262 - calcium channel activity
GO:0005385 - zinc ion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1401029

PK2L2
Polycystin-2-like protein 2

1

12

High-throughput

0.691

High

1401011

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

18

Small-scale

0.647

High

343450

SNP29
Synaptosomal-associated protein 29

3

0

High-throughput

0.638

High

1192282

ZACN
Ligand-gated cation channel ZACN

3

0

High-throughput

0.638

High

820723

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.618

High

845766

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.618

High

1401027

ARL15
ADP-ribosylation factor-like protein 15

3

4

High-throughput

0.609

High

1332397

PNDC1
Poly(A)-specific ribonuclease PNLDC1

2

0

High-throughput

0.602

High

540630

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.584

High

901505

RAB7A
Ras-related protein Rab-7a

2

4

High-throughput

0.584

High

978235

RHOB
Rho-related GTP-binding protein RhoB

2

10

High-throughput

0.584

High

761286

RYK
Tyrosine-protein kinase RYK

1

5

High-throughput

0.536

High

1095930

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

2

High-throughput

0.536

High

1195455

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

1

High-throughput

0.536

High

1203774

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1401018

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

417692

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

1

High-throughput

0.533

High

1401023

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1

4

Small-scale

0.527

High

1026940

PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

1

4

Small-scale

0.523

High

1154158

ITSN1
Intersectin-1

1

0

High-throughput

0.518

High

407207

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

1372460

TP4A1
Protein tyrosine phosphatase type IVA 1

1

0

High-throughput

0.513

High

619094

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

Small-scale

0.501

High

1034123

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

4

Small-scale

0.501

High

1162008

H31T
Histone H3.1t

1

1

Small-scale

0.501

High

961374

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.493

High

1357793

CC107
Coiled-coil domain-containing protein 107

1

1

High-throughput

0.489

High

1401020

RABE2
Rab GTPase-binding effector protein 2

1

12

High-throughput

0.489

High

388083

MBP
Myelin basic protein

1

0

Small-scale

0.480

High

126753

RHOD
Rho-related GTP-binding protein RhoD

1

13

High-throughput

0.479

High

164060

NDC80
Kinetochore protein NDC80 homolog

1

9

High-throughput

0.479

High

174059

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.479

High

341127

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.479

High

374147

RASN
GTPase NRas

1

12

High-throughput

0.479

High

374863

RASH
GTPase HRas

1

8

High-throughput

0.479

High

375853

RASK
GTPase KRas

1

12

High-throughput

0.479

High

439829

INSR
Insulin receptor

1

2

High-throughput

0.479

High

466422

RHOC
Rho-related GTP-binding protein RhoC

1

8

High-throughput

0.479

High

475666

K1C19
Keratin, type I cytoskeletal 19

1

1

High-throughput

0.479

High

562335

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

581240

RAC2
Ras-related C3 botulinum toxin substrate 2

1

8

High-throughput

0.479

High

601409

RHOQ
Rho-related GTP-binding protein RhoQ

1

10

High-throughput

0.479

High

604161

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

691352

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

730168

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.479

High

730841

1433S
14-3-3 protein sigma

1

6

High-throughput

0.479

High

900995

RAB5C
Ras-related protein Rab-5C

1

1

High-throughput

0.479

High

902018

RAB9A
Ras-related protein Rab-9A

1

5

High-throughput

0.479

High

910170

RND2
Rho-related GTP-binding protein RhoN

1

14

High-throughput

0.479

High

953623

RAC3
Ras-related C3 botulinum toxin substrate 3

1

9

High-throughput

0.479

High

955495

CDC42
Cell division control protein 42 homolog

1

10

High-throughput

0.479

High

956452

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

962400

RHOA
Transforming protein RhoA

1

9

High-throughput

0.479

High

962809

RND3
Rho-related GTP-binding protein RhoE

1

14

High-throughput

0.479

High

966773

1433G
14-3-3 protein gamma

1

6

High-throughput

0.479

High

975188

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

988626

RAC1
Ras-related C3 botulinum toxin substrate 1

1

9

High-throughput

0.479

High

990629

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.479

High

1015692

RHOG
Rho-related GTP-binding protein RhoG

1

8

High-throughput

0.479

High

1049690

1433F
14-3-3 protein eta

1

6

High-throughput

0.479

High

1058602

CKAP4
Cytoskeleton-associated protein 4

1

12

High-throughput

0.479

High

1110004

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.479

High

1125612

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

13

High-throughput

0.479

High

1145066

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1151826

RHOH
Rho-related GTP-binding protein RhoH

1

10

High-throughput

0.479

High

1270953

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.479

High

1322955

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1360918

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

1366866

RND1
Rho-related GTP-binding protein Rho6

1

14

High-throughput

0.479

High

1395918

DNJC1
DnaJ homolog subfamily C member 1

1

1

High-throughput

0.479

High

1396616

RHOV
Rho-related GTP-binding protein RhoV

1

10

High-throughput

0.479

High

1401013

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1401015

ESYT1
Extended synaptotagmin-1

1

4

High-throughput

0.479

High

1401019

RHOJ
Rho-related GTP-binding protein RhoJ

1

10

High-throughput

0.479

High

1401022

RHOF
Rho-related GTP-binding protein RhoF

1

12

High-throughput

0.479

High

1401030

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.479

High

1401034

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1401035

ALK
ALK tyrosine kinase receptor

1

2

High-throughput

0.479

High

1401036

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

189783

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

548363

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

580676

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

880652

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

894986

EMD
Emerin

1

0

High-throughput

0.458

High

904078

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

971906

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

1159808

OCLN
Occludin

1

0

High-throughput

0.458

High

1163401

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1238786

TECT3
Tectonic-3

1

0

High-throughput

0.458

High

1286877

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.458

High

1401012

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1401031

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

772968

MYH9
Myosin-9

1

10

Small-scale

0.445

High

773253

MYH10
Myosin-10

1

10

Small-scale

0.445

High

1277770

MYH14
Myosin-14

1

10

Small-scale

0.445

High

1353709

MOT10
Monocarboxylate transporter 10

1

1

High-throughput

0.445

High

1401032

S53A1
Solute carrier family 53 member 1

1

6

High-throughput

0.445

High

436977

K1C18
Keratin, type I cytoskeletal 18

1

1

High-throughput

0.437

High

611302

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.437

High

699029

CALX
Calnexin

1

1

High-throughput

0.437

High

847652

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.437

High

951365

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.437

High

1226231

CP135
Centrosomal protein of 135 kDa

1

9

High-throughput

0.437

High

1252186

SYNE3
Nesprin-3

1

10

High-throughput

0.437

High

1312226

MIRO2
Mitochondrial Rho GTPase 2

1

16

High-throughput

0.437

High

1381493

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.437

High

1401014

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1401026

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1401033

SEC63
Translocation protein SEC63 homolog

1

3

High-throughput

0.437

High

222317

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

1131597

MFS10
Major facilitator superfamily domain-containing protein 10

1

0

High-throughput

0.426

High

1236281

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

191974

TEX28
Testis-specific protein TEX28

2

0

High-throughput

0.328

High

291498

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

418373

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

1293644

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1333962

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

1352349

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low

1382915

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1383019

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.249

Low

1401016

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low

1401017

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1401021

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

1401024

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

1401025

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1401028

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

1401037

DJC16
DnaJ homolog subfamily C member 16

1

0

High-throughput

0.249

Low

1313979

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1395381

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025