Protein: FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)

Gene: FKB1A, FKBP1A
Organism: Homo sapiens
Interactions: 69
UniProt ID: P62942

Gene Ontology (top 5):
GO:0003007 - heart morphogenesis
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005160 - transforming growth factor beta receptor binding
GO:0005246 - calcium channel regulator activity
GO:0005527 - macrolide binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

839233

MTOR
Serine/threonine-protein kinase mTOR

16

8

Small-scale

0.984

High

787373

TGFR1
TGF-beta receptor type-1

6

7

Small-scale

0.944

High

641328

RYR1
Ryanodine receptor 1

4

10

Small-scale

0.893

High

787284

ACV1B
Activin receptor type-1B

2

7

Small-scale

0.805

High

986853

RYR3
Ryanodine receptor 3

2

9

Small-scale

0.778

High

986851

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

2

9

Small-scale

0.757

High

186531

TRI18
E3 ubiquitin-protein ligase Midline-1

2

10

High-throughput

0.754

High

410756

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

11

High-throughput

0.743

High

986852

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

9

High-throughput

0.743

High

986847

ACVR1
Activin receptor type-1

2

7

Small-scale

0.737

High

986845

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

2

16

Small-scale

0.712

High

986861

GLMN
Glomulin

3

3

Small-scale

0.667

High

641550

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

9

High-throughput

0.665

High

461340

HS90A
Heat shock protein HSP 90-alpha

1

20

Small-scale

0.647

High

787139

BMR1A
Bone morphogenetic protein receptor type-1A

1

7

Small-scale

0.621

High

986856

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

986860

RYR2
Ryanodine receptor 2

1

10

Small-scale

0.618

High

421882

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.611

High

822591

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.586

High

529563

TAU
Microtubule-associated protein tau

2

5

Small-scale

0.585

High

830520

CCNF
Cyclin-F

2

2

High-throughput

0.584

High

986857

RPTOR
Regulatory-associated protein of mTOR

2

8

Small-scale

0.584

High

376795

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

2

1

Small-scale

0.584

High

943899

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

10

High-throughput

0.575

High

717281

PEBP1
Phosphatidylethanolamine-binding protein 1

2

9

High-throughput

0.571

High

986846

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.561

High

788453

ACVL1
Activin receptor type-1-like

1

7

Small-scale

0.555

High

986866

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

10

High-throughput

0.553

High

986863

BARD1
BRCA1-associated RING domain protein 1

1

12

High-throughput

0.552

High

986873

AHSP
Alpha-hemoglobin-stabilizing protein

1

0

High-throughput

0.549

High

177668

SMAD7
Mothers against decapentaplegic homolog 7

1

1

Small-scale

0.543

High

986862

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.536

High

860138

RS9
Small ribosomal subunit protein uS4

1

2

High-throughput

0.515

High

354320

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.513

High

986858

DCA11
DDB1- and CUL4-associated factor 11

1

4

Small-scale

0.512

High

986872

NLGN3
Neuroligin-3

1

3

Small-scale

0.508

High

359802

DYR
Dihydrofolate reductase

1

1

Small-scale

0.501

High

955035

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.501

High

986871

ABI2
Abl interactor 2

1

2

High-throughput

0.481

High

229688

CALU
Calumenin

1

8

High-throughput

0.479

High

259760

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

538939

EPB41
Protein 4.1

1

1

High-throughput

0.479

High

762293

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

High-throughput

0.479

High

772137

MSX2
Homeobox protein MSX-2

1

2

High-throughput

0.479

High

887937

MCM2
DNA replication licensing factor MCM2

1

8

High-throughput

0.479

High

947146

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

4

High-throughput

0.479

High

986850

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

1

High-throughput

0.479

High

986859

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

986864

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

986865

YTHD1
YTH domain-containing family protein 1

1

4

High-throughput

0.479

High

986868

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

Small-scale

0.479

High

986874

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

986875

TRPC6
Short transient receptor potential channel 6

1

18

Small-scale

0.479

High

986877

YTHD2
YTH domain-containing family protein 2

1

3

High-throughput

0.479

High

347626

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

986848

REST
RE1-silencing transcription factor

1

0

High-throughput

0.458

High

219856

SMAD6
Mothers against decapentaplegic homolog 6

1

1

Small-scale

0.457

High

934422

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.445

High

675449

TYY1
Transcriptional repressor protein YY1

1

4

Small-scale

0.439

High

986854

SF3B4
Splicing factor 3B subunit 4

1

2

High-throughput

0.439

High

695162

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

767919

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

986849

TRPC3
Short transient receptor potential channel 3

1

12

Small-scale

0.437

High

986869

TRPC7
Short transient receptor potential channel 7

1

12

Small-scale

0.437

High

986876

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

986867

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

986870

DCA16
DDB1- and CUL4-associated factor 16

1

0

Small-scale

0.249

Low

986855

SHLD3
Shieldin complex subunit 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025