HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 16541103, 24981860, 35271311, 36325969, 35235311, 34349018, 37071682, 18628297, 26186194, 28514442, 33961781, 14688252
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4_WD40~eIF2A, eIF2A~WD40
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005852 - eukaryotic translation initiation factor 3 complex
and 6 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 814
Hs

1 325
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024