HitPredict

Interactor 1: LMAN1 (P49257)
Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Gp58) (Intracellular mannose-specific lectin MR60) (Lectin mannose-binding 1)
Gene: LMAN1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane GO:0007030 - Golgi organization GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 191
+	Hs
		880690 LMAN1_HUMAN (1-510): 0: 747: 100.00		RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17
+	Hs
		880512 LMAN1_HUMAN (1-510): 0: 747: 100.00		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		880517 LMAN1_HUMAN (1-510): 0: 747: 100.00		RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73
+	Hs
		880506 LMAN1_HUMAN (1-510): 0: 747: 100.00		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		580928 LMAN1_HUMAN (1-510): 0: 747: 100.00		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75
+	Hs
		466151 LMAN1_HUMAN (1-510): 0: 747: 100.00		RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41
+	Hs
		880502 LMAN1_HUMAN (1-510): 0: 747: 100.00		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32