HitPredict

Interactor 1: D3YT54 (D3YT54)
Rho-GAP domain-containing protein
Gene: srgp-1

Interactor 2: CDC42 (Q05062)
Cell division control protein 42 homolog (CDC42Ce)
Gene: cdc-42

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24632947
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005938 - cell cortex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 611 Ce			1 191
+	Ce
		88245 D3YT54_CAEEL (1-611): 2.27e-127: 389: 100.00		RAC1_CAEEL (1-191): 8.74e-83: 245: 70.68
+	Hs
		564562 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOQ_HUMAN (4-187): 3.27e-91: 266: 67.94
+	Hs
		925395 SRGP1_HUMAN (20-601): 1.88e-94: 315: 24.21		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11
+	Hs
		200213 SRGP3_HUMAN (20-594): 4.76e-92: 308: 24.12		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11
+	Hs
		1133703 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOJ_HUMAN (2-189): 5.52e-84: 248: 63.30
+	Hs
		900637 SRGP1_HUMAN (20-601): 1.88e-94: 315: 24.21		RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87
+	Hs
		925343 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11
+	Mm
		1194500 RHG33_MOUSE (4-587): 3.71e-86: 294: 15.28		RHOJ_MOUSE (2-179): 8.06e-83: 246: 64.61
+	Hs
		925354 RHG17_HUMAN (57-611): 2.01e-88: 294: 16.61		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11
+	Hs
		951062 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOG_HUMAN (1-191): 5.85e-79: 235: 58.12
+	Mm
		892733 SRGP1_MOUSE (20-601): 4.05e-89: 300: 23.42		CDC42_MOUSE (1-191): 2.71e-78: 233: 86.39
+	Hs
		894109 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39
+	Hs
		900540 RHG29_HUMAN (2-596): 4.69e-89: 302: 14.62		RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87
+	Mm
		1265268 SRGP1_MOUSE (20-601): 4.05e-89: 300: 23.42		RHOA_MOUSE (5-191): 8.36e-78: 232: 52.41
+	Hs
		545426 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71
+	Hs
		900564 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87
+	Hs
		892420 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RAC3_HUMAN (1-177): 5.96e-76: 227: 70.62
+	Mm
		892729 RHG33_MOUSE (4-587): 3.71e-86: 294: 15.28		CDC42_MOUSE (1-191): 2.71e-78: 233: 86.39
+	Hs
		894126 RHG17_HUMAN (57-611): 2.01e-88: 294: 16.61		CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39
+	Hs
		147862 RHG33_HUMAN (4-589): 2.25e-82: 283: 14.66		RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11