HitPredict

Interactor 1: H2BFS (P57053)
Histone H2B type F-S (H2B-clustered histone 12 like) (H2B.S histone 1) (Histone H2B.s) (H2B/s)
Gene: H2BC12L

Interactor 2: PWP2A (Q96N64)
PWWP domain-containing protein 2A
Gene: PWWP2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 755
+	Hs
		1087347 H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83		PWP2A_HUMAN (1-755): 5.64e-106: 343: 100.00
+	Hs
		1274415 H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83		PWP2A_HUMAN (1-755): 5.64e-106: 343: 100.00
+	Hs
		241613 H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41		PWP2A_HUMAN (1-755): 5.64e-106: 343: 100.00
+	Hs
		918616 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		PWP2A_HUMAN (1-755): 5.64e-106: 343: 100.00
+	Hs
		918802 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		DNM3A_HUMAN (331-739): 1.19e-71: 253: 15.88
+	Hs
		1087508 H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83		CRBG1_HUMAN (7-679): 5.54e-28: 123: 12.91
+	Hs
		1087196 H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83		NIPBL_HUMAN (230-664): 2.34e-15: 82.8: 13.39
+	Hs
		918442 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		NIPBL_HUMAN (230-664): 2.34e-15: 82.8: 13.39
+	Hs
		1056847 H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		1056919 H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		707631 H2B1B_HUMAN (1-126): 1.07e-53: 166: 95.24		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		918364 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		1129830 H2B2F_HUMAN (1-126): 1.57e-54: 168: 96.03		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		617962 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		1087299 H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		1264778 H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		883041 H2BFS_HUMAN (1-126): 2.65e-54: 167: 100.00		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		241595 H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		918561 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		886166 H2B1D_HUMAN (1-126): 1.97e-53: 165: 96.83		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97