HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 412
+	Hs
		1053188 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		883470 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKB1A_HUMAN (101-204): 1.72e-35: 128: 32.41
+	Hs
		883489 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		923838 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKB1A_HUMAN (101-204): 1.72e-35: 128: 32.41
+	Hs
		684571 RIPK4_HUMAN (1-832): 0: 726: 100.00		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		883504 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		972586 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		685027 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		1034995 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		556701 ANK1_HUMAN (233-737): 6.25e-92: 319: 21.44		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		684893 ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		1034933 ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		972616 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		685142 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		1035071 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21