HitPredict

Interactor 1: SYJ2B (P57105)
Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25)
Gene: SYNJ2BP

Interactor 2: DLL4 (Q9NR61)
Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4)
Gene: DLL4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24025447
Identification Methods	luminescence based mammalian interactome mapping, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010596 - negative regulation of endothelial cell migration
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 145 Hs			1 685
+	Mm
		1322068 SYJ2B_MOUSE (1-145): 6.21e-45: 145: 91.03		DLL4_MOUSE (20-685): 9.4e-109: 346: 86.94
+	Hs
		132253 SYJ2B_HUMAN (1-145): 1.52e-45: 147: 100.00		DLL1_HUMAN (22-685): 5.49e-81: 273: 46.64
+	Mm
		1322297 MAGI3_MOUSE (16-109): 1.02e-14: 71.9: 26.04		DLL4_MOUSE (20-685): 9.4e-109: 346: 86.94
+	Mm
		1257409 MPDZ_MOUSE (19-103): 1.07e-12: 66.1: 23.53		DLL4_MOUSE (20-685): 9.4e-109: 346: 86.94
+	Mm
		1142613 SYJ2B_MOUSE (1-145): 6.21e-45: 145: 91.03		DLL1_MOUSE (6-685): 3.59e-78: 266: 46.23
+	Mm
		1142614 MAGI3_MOUSE (16-109): 1.02e-14: 71.9: 26.04		DLL1_MOUSE (6-685): 3.59e-78: 266: 46.23
+	Mm
		1142611 MPDZ_MOUSE (19-103): 1.07e-12: 66.1: 23.53		DLL1_MOUSE (6-685): 3.59e-78: 266: 46.23
+	Dm
		113606 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		Q9VTP0_DROME (404-607): 2.89e-26: 117: 19.48
+	Mm
		82714 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		B9EJ72_MOUSE (9-271): 2.46e-18: 92.3: 10.55
+	Hs
		1049987 SCRIB_HUMAN (12-97): 7.85e-11: 60.5: 39.33		DLK2_HUMAN (309-546): 3.76e-30: 124: 37.71
+	Dm
		113054 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		TENM_DROME (20-207): 1.09e-10: 67.6: 8.66
+	Hs
		946788 INADL_HUMAN (14-100): 4.42e-13: 66.9: 28.41		CRUM1_HUMAN (438-573): 8.45e-10: 64.5: 22.79