HitPredict

Interactor 1: RAB25 (P57735)
Ras-related protein Rab-25 (CATX-8)
Gene: RAB25

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005794 - Golgi apparatus GO:0031489 - myosin V binding GO:0055037 - recycling endosome and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 218
+	Hs
		918879 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		913992 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		914093 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Zm
		73944 B4FAE1_MAIZE (6-211): 2.22e-90: 265: 40.78		B4FAE1_MAIZE (4-216): 1.33e-89: 263: 44.13
+	Hs
		913989 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Mm
		914510 RB11A_MOUSE (1-213): 1.11e-87: 259: 60.37		RB11A_MOUSE (1-218): 1.25e-91: 269: 90.37
+	Hs
		918846 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		918944 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Mm
		919000 RAB1A_MOUSE (1-210): 3.08e-89: 262: 39.05		RAB1B_MOUSE (4-215): 3.54e-86: 255: 44.81
+	Hs
		1079964 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Zm
		75506 B4FJ62_MAIZE (1-212): 1.65e-87: 258: 53.95		B4FJ62_MAIZE (1-217): 9.43e-87: 257: 66.06
+	Hs
		884467 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		884466 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		918916 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB2B_HUMAN (8-178): 1.08e-61: 193: 56.14
+	Hs
		895026 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895264 RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56