HitPredict

Interactor 1: FBXW4 (P57775)
F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)
Gene: FBXW4

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 23658844
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 543
+	Hs
		903467 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1202777 WDR5B_HUMAN (33-319): 2.7e-61: 203: 12.80		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826588 FBXW4_HUMAN (21-412): 3.66e-83: 262: 98.22		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821142 FBXW4_HUMAN (21-412): 3.66e-83: 262: 98.22		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573190 FBXW4_HUMAN (21-412): 3.66e-83: 262: 98.22		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		792942 LIS1_HUMAN (7-322): 9.15e-67: 219: 13.20		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826601 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826748 WDR5B_HUMAN (33-319): 2.7e-61: 203: 12.80		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821152 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573201 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573346 WDR5B_HUMAN (33-319): 2.7e-61: 203: 12.80		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826807 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826772 POC1A_HUMAN (22-227): 1.35e-37: 142: 11.27		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573406 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821316 POC1A_HUMAN (22-227): 1.35e-37: 142: 11.27		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573371 POC1A_HUMAN (22-227): 1.35e-37: 142: 11.27		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843127 FBXW4_HUMAN (21-412): 3.66e-83: 262: 98.22		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843139 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843273 WDR5B_HUMAN (33-319): 2.7e-61: 203: 12.80		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843289 POC1A_HUMAN (22-227): 1.35e-37: 142: 11.27		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79