Protein: IBP3
Insulin-like growth factor-binding protein 3 (IBP-3) (IGF-binding protein 3) (IGFBP-3)

Gene: IBP3, IGFBP3
Organism: Homo sapiens
Interactions: 62
UniProt ID: P17936

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001558 - regulation of cell growth
GO:0001649 - osteoblast differentiation
GO:0001933 - negative regulation of protein phosphorylation
GO:0001968 - fibronectin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

392950

IGF1
Insulin-like growth factor I

7

10

Small-scale

0.963

High

352346

IGF2
Insulin-like growth factor II

5

10

Small-scale

0.919

High

364522

TRFE
Serotransferrin

1

0

Small-scale

0.687

High

362791

FINC
Fibronectin

2

6

Small-scale

0.636

High

197584

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

2

3

Small-scale

0.625

High

572494

IBP3
Insulin-like growth factor-binding protein 3

1

12

Small-scale

0.618

High

572501

ALS
Insulin-like growth factor-binding protein complex acid labile subunit

2

2

Small-scale

0.602

High

358469

CO1A1
Collagen alpha-1(I) chain

1

5

Small-scale

0.581

High

572517

TM219
Insulin-like growth factor-binding protein 3 receptor

1

0

Small-scale

0.561

High

572495

RXRA
Retinoic acid receptor RXR-alpha

1

2

Small-scale

0.561

High

572515

NONO
Non-POU domain-containing octamer-binding protein

1

1

Small-scale

0.561

High

341356

PLMN
Plasminogen

1

4

Small-scale

0.550

High

555072

CD44
CD44 antigen

2

2

Small-scale

0.550

High

210981

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

1

High-throughput

0.541

High

349859

RASK
GTPase KRas

1

2

High-throughput

0.541

High

572518

HUNIN
Humanin

1

0

Small-scale

0.537

High

572508

LRP2
Low-density lipoprotein receptor-related protein 2

1

4

High-throughput

0.536

High

160370

AURKA
Aurora kinase A

1

0

High-throughput

0.518

High

572499

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.518

High

572502

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.518

High

572516

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.518

High

572522

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.518

High

572528

MLH3
DNA mismatch repair protein Mlh3

1

0

High-throughput

0.518

High

572529

RA54B
DNA repair and recombination protein RAD54B

1

0

High-throughput

0.518

High

572514

SETB1
Histone-lysine N-methyltransferase SETDB1

1

3

High-throughput

0.515

High

572524

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.513

High

572526

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

0

High-throughput

0.513

High

572527

STK26
Serine/threonine-protein kinase 26

1

0

High-throughput

0.513

High

572503

PPARG
Peroxisome proliferator-activated receptor gamma

1

5

Small-scale

0.501

High

572513

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

18

Small-scale

0.501

High

572519

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

2

Small-scale

0.501

High

572525

PAPP2
Pappalysin-2

1

4

Small-scale

0.501

High

337901

EGFR
Epidermal growth factor receptor

1

5

Small-scale

0.500

High

572509

TF3C1
General transcription factor 3C polypeptide 1

1

1

High-throughput

0.494

High

566274

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.493

High

572520

LMO3
LIM domain only protein 3

1

0

High-throughput

0.493

High

572521

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.493

High

309441

MTMR5
Myotubularin-related protein 5

1

1

High-throughput

0.489

High

572510

MTMR1
Myotubularin-related protein 1

1

1

High-throughput

0.489

High

373646

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

408997

K2C8
Keratin, type II cytoskeletal 8

1

1

Small-scale

0.479

High

434931

SP1
Transcription factor Sp1

1

3

Small-scale

0.479

High

444527

K2C7
Keratin, type II cytoskeletal 7

1

1

Small-scale

0.479

High

564791

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

Small-scale

0.479

High

569146

CEBPB
CCAAT/enhancer-binding protein beta

1

2

Small-scale

0.479

High

572496

HNF1A
Hepatocyte nuclear factor 1-alpha

1

1

Small-scale

0.479

High

572498

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

Small-scale

0.479

High

572500

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

1

15

Small-scale

0.479

High

572504

ACTB
Actin, cytoplasmic 1

1

2

Small-scale

0.479

High

572505

1433G
14-3-3 protein gamma

1

4

High-throughput

0.470

High

345870

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

386055

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

398824

HMGN2
Non-histone chromosomal protein HMG-17

1

0

Small-scale

0.458

High

572497

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

Small-scale

0.458

High

572506

H4
Histone H4

1

0

Small-scale

0.458

High

572523

H2A1H
Histone H2A type 1-H

1

0

Small-scale

0.458

High

435528

IGF1R
Insulin-like growth factor 1 receptor

1

5

Small-scale

0.445

High

572507

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

Small-scale

0.445

High

572511

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.282

High

572512

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.279

Low

444308

K1C19
Keratin, type I cytoskeletal 19

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024