HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: RSC4 (Q02206)
Chromatin structure-remodeling complex subunit RSC4 (RSC complex subunit RSC4) (Remodel the structure of chromatin complex subunit 4)
Gene: RSC4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Sc			1 625
+	Hs
		846794 ACTBL_HUMAN (2-375): 0: 687: 83.42		SMCA2_HUMAN (78-148): 9.33e-12: 70.5: 34.72
+	Dm
		501486 ACT1_DROME (2-375): 0: 596: 89.31		BRM_DROME (166-291): 1.07e-32: 137: 29.37
+	Dm
		361138 ACT2_DROME (2-375): 0: 594: 88.77		BRM_DROME (166-291): 1.07e-32: 137: 29.37
+	Hs
		891726 ACTB_HUMAN (1-375): 0: 601: 88.80		EP300_HUMAN (4-210): 2.62e-21: 101: 14.35
+	Xl
		292752 ACTB_XENLA (1-375): 0: 600: 88.80		Q4VQ79_XENLA (3-210): 6.72e-20: 96.9: 18.69
+	Sc
		728733 ACT_YEAST (1-375): 0: 594: 100.00		BDF1_YEAST (117-384): 5.12e-22: 102: 15.22
+	Hs
		932966 ACTS_HUMAN (2-375): 0: 590: 86.90		EP300_HUMAN (4-210): 2.62e-21: 101: 14.35
+	Hs
		915369 ACTA_HUMAN (2-375): 0: 589: 86.63		EP300_HUMAN (4-210): 2.62e-21: 101: 14.35
+	Sc
		887658 ACT_YEAST (1-375): 0: 594: 100.00		GCN5_YEAST (5-160): 4.11e-20: 95.3: 16.77
+	Hs
		891942 ACTB_HUMAN (1-375): 0: 601: 88.80		CBP_HUMAN (2-161): 8.96e-14: 77.2: 17.06
+	Mm
		929795 ACTG_MOUSE (1-375): 0: 600: 89.07		SMCA2_MOUSE (56-148): 4.3e-14: 78.2: 32.32
+	Hs
		846910 ACTB_HUMAN (1-375): 0: 601: 88.80		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Mm
		929785 ACTG_MOUSE (1-375): 0: 600: 89.07		SMCA4_MOUSE (56-148): 2.07e-12: 72.8: 33.33
+	Hs
		846917 ACTG_HUMAN (1-375): 0: 600: 89.07		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		244258 ACTG_HUMAN (1-375): 0: 600: 89.07		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05
+	Hs
		846918 ACTC_HUMAN (2-375): 0: 591: 87.17		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		846919 ACTS_HUMAN (2-375): 0: 590: 86.90		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		846742 ACTC_HUMAN (2-375): 0: 591: 87.17		SMCA2_HUMAN (78-148): 9.33e-12: 70.5: 34.72
+	Hs
		244261 ACTC_HUMAN (2-375): 0: 591: 87.17		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05
+	Rn
		892233 ACTB_RAT (1-375): 0: 601: 88.80		Q6AYL3_RAT (7-106): 5.41e-09: 60: 14.71