Protein: DAG1
Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]

Gene: DAG1
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q14118

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001618 - virus receptor activity
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0002009 - morphogenesis of an epithelium
GO:0002011 - morphogenesis of an epithelial sheet

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1120608

DAG1
Dystroglycan 1

2

7

Small-scale

0.812

High

862647

UTRN
Utrophin

4

7

Small-scale

0.702

High

125449

LEG9
Galectin-9

3

5

High-throughput

0.667

High

127330

LEG8
Galectin-8

3

5

High-throughput

0.667

High

378089

TNFA
Tumor necrosis factor

3

1

High-throughput

0.667

High

1120618

CEA21
Cell adhesion molecule CEACAM21

3

2

High-throughput

0.667

High

547446

DMD
Dystrophin

3

7

Small-scale

0.651

High

1120628

KIBRA
Protein KIBRA

3

7

Small-scale

0.650

High

375507

RASK
GTPase KRas

3

10

High-throughput

0.640

High

627526

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

0

High-throughput

0.638

High

1120635

5HT3C
5-hydroxytryptamine receptor 3C

3

0

High-throughput

0.638

High

1120650

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.638

High

557297

SRC
Proto-oncogene tyrosine-protein kinase Src

2

10

Small-scale

0.634

High

749770

CADH5
Cadherin-5

2

7

High-throughput

0.628

High

1120609

I13R2
Interleukin-13 receptor subunit alpha-2

2

2

High-throughput

0.628

High

1120655

PCDGG
Protocadherin gamma-B4

2

6

High-throughput

0.628

High

1120657

PCDBB
Protocadherin beta-11

2

6

High-throughput

0.628

High

1120659

PCDG5
Protocadherin gamma-A5

2

6

High-throughput

0.628

High

1120662

PCDC2
Protocadherin alpha-C2

2

6

High-throughput

0.628

High

440554

FYN
Tyrosine-protein kinase Fyn

2

9

Small-scale

0.624

High

593991

NCK1
SH2/SH3 adapter protein NCK1

2

20

Small-scale

0.624

High

987627

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.624

High

1120621

LEG9C
Galectin-9C

2

5

High-throughput

0.611

High

333753

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

2

0

High-throughput

0.602

High

749328

TNFL8
Tumor necrosis factor ligand superfamily member 8

2

0

High-throughput

0.602

High

1120642

TECT2
Tectonic-2

2

0

High-throughput

0.602

High

1120658

PCDG9
Protocadherin gamma-A9

2

6

High-throughput

0.601

High

1041056

CAV1
Caveolin-1

2

4

Small-scale

0.595

High

136894

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

2

9

Small-scale

0.585

High

183251

LAMA5
Laminin subunit alpha-5

2

9

Small-scale

0.585

High

373924

RASN
GTPase NRas

2

10

High-throughput

0.584

High

540447

LAMP1
Lysosome-associated membrane glycoprotein 1

2

1

High-throughput

0.584

High

978000

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

353319

AGR2
Anterior gradient protein 2 homolog

2

3

Small-scale

0.584

High

1120626

TBA1A
Tubulin alpha-1A chain

1

1

Small-scale

0.578

High

1120653

FBX2
F-box only protein 2

2

0

High-throughput

0.576

High

762319

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

2

1

Small-scale

0.571

High

431808

ITB1
Integrin beta-1

1

4

Small-scale

0.561

High

536340

MTAP2
Microtubule-associated protein 2

1

11

Small-scale

0.561

High

555680

ACTN1
Alpha-actinin-1

1

5

Small-scale

0.561

High

613349

VINC
Vinculin

1

2

Small-scale

0.561

High

711348

SHC1
SHC-transforming protein 1

1

8

Small-scale

0.561

High

834188

CSK
Tyrosine-protein kinase CSK

1

11

Small-scale

0.561

High

941345

CAV3
Caveolin-3

1

4

Small-scale

0.561

High

275811

CAD16
Cadherin-16

1

6

High-throughput

0.536

High

480791

LEG1
Galectin-1

1

5

High-throughput

0.536

High

539702

ACHB
Acetylcholine receptor subunit beta

1

2

High-throughput

0.536

High

548015

PSPC
Surfactant protein C

1

1

High-throughput

0.536

High

731844

CEAM8
Cell adhesion molecule CEACAM8

1

3

High-throughput

0.536

High

761222

RYK
Tyrosine-protein kinase RYK

1

9

High-throughput

0.536

High

1048789

ACHE
Acetylcholine receptor subunit epsilon

1

2

High-throughput

0.536

High

1120614

SGCA
Alpha-sarcoglycan

1

2

High-throughput

0.536

High

1120617

HFE
Hereditary hemochromatosis protein

1

1

High-throughput

0.536

High

1120619

EGFLA
Pikachurin

1

10

High-throughput

0.536

High

1120622

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.536

High

1120624

BTNL3
Butyrophilin-like protein 3

1

3

High-throughput

0.536

High

1120649

CBLN4
Cerebellin-4

1

4

High-throughput

0.536

High

1120652

BTNL2
Butyrophilin-like protein 2

1

6

High-throughput

0.536

High

1120660

PCDG4
Protocadherin gamma-A4

1

6

High-throughput

0.536

High

1120661

PCDA8
Protocadherin alpha-8

1

6

High-throughput

0.536

High

105913

APRIO
Alternative prion protein

2

3

Small-scale

0.533

High

253435

CST8
Cystatin-8

1

0

High-throughput

0.513

High

518840

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.513

High

749202

CD70
CD70 antigen

1

0

High-throughput

0.513

High

1120612

NPTX1
Neuronal pentraxin-1

1

0

High-throughput

0.513

High

1120616

CL12B
C-type lectin domain family 12 member B

1

0

High-throughput

0.513

High

1120634

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.513

High

1120638

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1120639

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

1120641

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

1120643

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.513

High

1120645

TMPSD
Transmembrane protease serine 13

1

0

High-throughput

0.513

High

1120663

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.513

High

481278

HMGB1
High mobility group protein B1

1

2

Small-scale

0.508

High

663818

LAMA2
Laminin subunit alpha-2

1

9

Small-scale

0.501

High

1120656

TLN1
Talin-1

1

4

Small-scale

0.501

High

262384

DTNB
Dystrobrevin beta

1

6

Small-scale

0.484

High

641951

CD9
CD9 antigen

1

4

High-throughput

0.484

High

1104820

SNTB2
Beta-2-syntrophin

1

6

Small-scale

0.484

High

1106463

DRP2
Dystrophin-related protein 2

1

9

Small-scale

0.481

High

1116801

RAPSN
43 kDa receptor-associated protein of the synapse

1

2

Small-scale

0.481

High

1120632

AGR3
Anterior gradient protein 3

1

3

Small-scale

0.481

High

889979

PSN1
Presenilin-1

1

0

Small-scale

0.479

High

1120636

NICA
Nicastrin

1

0

Small-scale

0.479

High

126589

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

218168

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

374593

RASH
GTPase HRas

1

8

High-throughput

0.479

High

466244

RHOC
Rho-related GTP-binding protein RhoC

1

18

High-throughput

0.479

High

556073

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

581037

RAC2
Ras-related C3 botulinum toxin substrate 2

1

16

High-throughput

0.479

High

601282

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

710235

EPHA2
Ephrin type-A receptor 2

1

6

High-throughput

0.479

High

774349

BASI
Basigin

1

2

High-throughput

0.479

High

799096

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

845636

MUC18
Cell surface glycoprotein MUC18

1

6

High-throughput

0.479

High

953438

RAC3
Ras-related C3 botulinum toxin substrate 3

1

18

High-throughput

0.479

High

955152

CDC42
Cell division control protein 42 homolog

1

19

High-throughput

0.479

High

962036

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

988356

RAC1
Ras-related C3 botulinum toxin substrate 1

1

19

High-throughput

0.479

High

1004548

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1015429

RHOG
Rho-related GTP-binding protein RhoG

1

17

High-throughput

0.479

High

1050990

FAK1
Focal adhesion kinase 1

1

15

Small-scale

0.479

High

1120610

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

1120611

RHOH
Rho-related GTP-binding protein RhoH

1

19

High-throughput

0.479

High

1120625

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1120627

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.479

High

1120631

TET1
Methylcytosine dioxygenase TET1

1

1

High-throughput

0.479

High

1120640

SH3K1
SH3 domain-containing kinase-binding protein 1

1

15

High-throughput

0.479

High

1120644

PRAX
Periaxin

1

4

Small-scale

0.479

High

1120646

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

Small-scale

0.479

High

1120647

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1120648

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

699743

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.458

High

1120615

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1120620

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1120623

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

190224

MOT4
Monocarboxylate transporter 4

1

1

High-throughput

0.445

High

220127

SGCE
Epsilon-sarcoglycan

1

2

Small-scale

0.445

High

330149

VENTX
Homeobox protein VENTX

1

3

High-throughput

0.445

High

349418

TSN15
Tetraspanin-15

1

4

High-throughput

0.445

High

362035

AATM
Aspartate aminotransferase, mitochondrial

1

1

Small-scale

0.445

High

462876

LAMB1
Laminin subunit beta-1

1

6

Small-scale

0.445

High

529776

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.445

High

535047

BIP
Endoplasmic reticulum chaperone BiP

1

2

Small-scale

0.445

High

551708

HARS1
Histidine--tRNA ligase, cytoplasmic

1

1

Small-scale

0.445

High

566664

PDIA4
Protein disulfide-isomerase A4

1

2

Small-scale

0.445

High

568145

PLSL
Plastin-2

1

5

Small-scale

0.445

High

602785

AATC
Aspartate aminotransferase, cytoplasmic

1

1

Small-scale

0.445

High

671790

ZA2G
Zinc-alpha-2-glycoprotein

1

1

Small-scale

0.445

High

681159

PSA2
Proteasome subunit alpha type-2

1

1

Small-scale

0.445

High

700881

PSB4
Proteasome subunit beta type-4

1

2

Small-scale

0.445

High

868689

LEG7
Galectin-7

1

5

Small-scale

0.445

High

887652

PSB2
Proteasome subunit beta type-2

1

1

Small-scale

0.445

High

948824

CD81
CD81 antigen

1

4

High-throughput

0.445

High

979636

H4
Histone H4

1

3

Small-scale

0.445

High

1066298

RBBP4
Histone-binding protein RBBP4

1

3

Small-scale

0.445

High

1120613

SGCB
Beta-sarcoglycan

1

3

Small-scale

0.445

High

1120637

SGCD
Delta-sarcoglycan

1

3

Small-scale

0.445

High

1120651

GPC5B
G-protein coupled receptor family C group 5 member B

1

1

High-throughput

0.445

High

1120654

KDIS
Kinase D-interacting substrate of 220 kDa

1

5

Small-scale

0.445

High

190606

MRP4
ATP-binding cassette sub-family C member 4

1

0

Small-scale

0.426

High

399972

CATA
Catalase

1

0

Small-scale

0.426

High

467482

4F2
Amino acid transporter heavy chain SLC3A2

1

0

Small-scale

0.426

High

828650

MDHC
Malate dehydrogenase, cytoplasmic

1

0

Small-scale

0.426

High

880447

RPIA
Ribose-5-phosphate isomerase

1

0

Small-scale

0.426

High

949150

TPIS
Triosephosphate isomerase

1

0

Small-scale

0.426

High

1120633

POF1B
Protein POF1B

1

0

Small-scale

0.426

High

1120629

TTC9C
Tetratricopeptide repeat protein 9C

1

1

High-throughput

0.407

High

1103956

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1120630

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025