HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 10944111, 16429126
Identification Methods two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Myosin_head
Common GO terms GO:0005524 - ATP binding
GO:0006897 - endocytosis
GO:0016787 - hydrolase activity
GO:0030479 - actin cortical patch
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 375
Sc

1 1219
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024