Interactor 1: D3ZV15 (D3ZV15)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: Cbl

Interactor 2: Q9QX70 (Q9QX70)
Receptor protein-tyrosine kinase (EC 2.7.10.1)
Gene: Egfr

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 20029031, 8550620
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007166 - cell surface receptor signaling pathway
GO:0019901 - protein kinase binding
GO:0042059 - negative regulation of epidermal growth factor receptor signaling pathway
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 894
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1 1209
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Last updated: 15 Jul 2024