HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: GPR35 (Q9HC97)
G-protein coupled receptor 35 (Kynurenic acid receptor) (KYNA receptor)
Gene: GPR35

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 236 Hs			1 309
+	Hs
		673752 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		BKRB2_HUMAN (1-287): 2.38e-74: 235: 25.82
+	Hs
		849732 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CCR9_HUMAN (10-301): 1.17e-72: 230: 22.83
+	Hs
		428997 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		ADRB2_HUMAN (2-307): 8.28e-67: 216: 14.33
+	Hs
		783813 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CCR2_HUMAN (9-297): 1.92e-66: 214: 18.94
+	Hs
		783911 TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31		CCR9_HUMAN (10-301): 1.17e-72: 230: 22.83
+	Hs
		722930 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		ADA1A_HUMAN (3-308): 2.11e-64: 211: 18.99
+	Hs
		783922 TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31		GPR35_HUMAN (1-309): 5.97e-71: 223: 100.00
+	Hs
		653086 CD82_HUMAN (4-234): 1.57e-49: 164: 23.11		BKRB2_HUMAN (1-287): 2.38e-74: 235: 25.82
+	Hs
		428955 TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31		ADRB2_HUMAN (2-307): 8.28e-67: 216: 14.33
+	Hs
		783809 TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31		CCR2_HUMAN (9-297): 1.92e-66: 214: 18.94
+	Hs
		326064 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		GPR17_HUMAN (4-292): 6.71e-78: 243: 27.82
+	Hs
		428918 CD9_HUMAN (1-234): 3.88e-53: 172: 43.59		ADRB2_HUMAN (2-307): 8.28e-67: 216: 14.33
+	Hs
		326045 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		CCR6_HUMAN (14-309): 6.89e-75: 235: 23.10
+	Hs
		237794 TSN3_HUMAN (4-236): 1.19e-43: 149: 18.88		CCR6_HUMAN (14-309): 6.89e-75: 235: 23.10
+	Hs
		237791 TSN3_HUMAN (4-236): 1.19e-43: 149: 18.88		OPRX_HUMAN (2-306): 3.38e-64: 208: 24.06
+	Hs
		208446 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		OX2R_HUMAN (15-307): 4.45e-62: 205: 18.05
+	Hs
		502891 CD37_HUMAN (2-232): 3.4e-44: 151: 20.00		AGTR1_HUMAN (10-309): 9.54e-62: 201: 21.12
+	Hs
		326031 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		NK3R_HUMAN (7-294): 1.51e-60: 201: 18.89
+	Hs
		326034 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		AGTR1_HUMAN (10-309): 9.54e-62: 201: 21.12
+	Hs
		326039 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		LPAR6_HUMAN (27-286): 4.94e-34: 129: 30.61