HitPredict

Interactor 1: EIF3E (P60228)
Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48)
Gene: EIF3E

Interactor 2: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 24981860
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0005829 - cytosol GO:0006413 - translational initiation GO:0006446 - regulation of translational initiation
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 407
+	Hs
		888327 EIF3E_HUMAN (1-445): 0: 680: 100.00		IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88
+	Hs
		133949 EIF3E_HUMAN (1-445): 0: 680: 100.00		DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51