HitPredict

Interactor 1: RBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)
Gene: RANBP2

Interactor 2: RGPD5 (Q99666)
RANBP2-like and GRIP domain-containing protein 5/6 (Ran-binding protein 2-like 1/2) (RanBP2-like 1/2) (RanBP2L1) (RanBP2L2) (Sperm membrane protein BS-63)
Gene: RGPD5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ran_BP1~Ran_BP1
Common GO terms	GO:0005643 - nuclear pore GO:0005737 - cytoplasm GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 3224 Hs			1 1765
+	Hs
		161597 RBP2_HUMAN (1-3224): 0: 2997: 100.00		RGPD8_HUMAN (1-1765): 0: 2162: 99.49
+	Hs
		515816 RBP2_HUMAN (1-3224): 0: 2997: 100.00		RGPD2_HUMAN (1-1760): 0: 2110: 93.41
+	Hs
		66742 RBP2_HUMAN (1-3224): 0: 2997: 100.00		RGPD3_HUMAN (1-1757): 0: 2109: 95.56
+	Hs
		890521 RBP2_HUMAN (1-3224): 0: 2997: 100.00		RGPD4_HUMAN (1-1757): 0: 2104: 95.05
+	Hs
		515779 RBP2_HUMAN (1-3224): 0: 2997: 100.00		RGPD1_HUMAN (26-1760): 0: 2095: 93.83
+	Hs
		890614 RBP2_HUMAN (1-3224): 0: 2997: 100.00		NUP50_HUMAN (1124-1466): 1.63e-33: 138: 18.68
+	Hs
		890422 RBP2_HUMAN (1-3224): 0: 2997: 100.00		RBP2_HUMAN (686-1191): 1.36e-30: 134: 23.67
+	Hs
		849306 RBP2_HUMAN (1-3224): 0: 2997: 100.00		RANG_HUMAN (1014-1207): 2.49e-27: 113: 37.88
+	Hs
		1277160 RGPD4_HUMAN (2364-3064): 2.46e-43: 177: 18.98		RGPD5_HUMAN (1-1765): 0: 2162: 100.00
+	Hs
		161626 RGPD4_HUMAN (2364-3064): 2.46e-43: 177: 18.98		RGPD8_HUMAN (1-1765): 0: 2162: 99.49
+	Hs
		161587 RGPD1_HUMAN (2377-3064): 1.66e-41: 171: 18.11		RGPD8_HUMAN (1-1765): 0: 2162: 99.49
+	Hs
		515826 RGPD4_HUMAN (2364-3064): 2.46e-43: 177: 18.98		RGPD2_HUMAN (1-1760): 0: 2110: 93.41
+	Hs
		66756 RGPD4_HUMAN (2364-3064): 2.46e-43: 177: 18.98		RGPD3_HUMAN (1-1757): 0: 2109: 95.56
+	Hs
		515769 RGPD1_HUMAN (2377-3064): 1.66e-41: 171: 18.11		RGPD2_HUMAN (1-1760): 0: 2110: 93.41
+	Hs
		66733 RGPD1_HUMAN (2377-3064): 1.66e-41: 171: 18.11		RGPD3_HUMAN (1-1757): 0: 2109: 95.56
+	Hs
		515796 RGPD4_HUMAN (2364-3064): 2.46e-43: 177: 18.98		RGPD1_HUMAN (26-1760): 0: 2095: 93.83
+	Hs
		515768 RGPD1_HUMAN (2377-3064): 1.66e-41: 171: 18.11		RGPD1_HUMAN (26-1760): 0: 2095: 93.83