HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	25771791, 32296183, 32296703, 25416956, 16189514, 33545068, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000421 - autophagosome membrane GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Hs			1 446
+	Hs
		306150 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		1025551 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		1025542 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		1025553 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		1025548 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		891207 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		306222 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		1201905 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		1201898 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		1201902 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		891347 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07
+	Hs
		306342 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07
+	Hs
		725011 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		1328053 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07
+	Hs
		944705 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		MAP1A_HUMAN (159-425): 1.97e-12: 71.7: 12.64
+	Hs
		944703 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		MAP1A_HUMAN (159-425): 1.97e-12: 71.7: 12.64
+	Hs
		1051455 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83
+	Hs
		1315808 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07
+	Hs
		1330650 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07
+	Hs
		1326188 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		CACO1_HUMAN (91-407): 9.18e-09: 59.7: 14.07