HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: TBCD5 (Q92609)
TBC1 domain family member 5
Gene: TBC1D5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

Property	Details
Experiments	25416956, 16189514, 32296183, unassigned1304, 31515488
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0006914 - autophagy GO:0015031 - protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Hs			1 795
+	Hs
		82491 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		B9A6K1_HUMAN (1-795): 0: 706: 100.00
+	Hs
		1267955 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TBCD5_HUMAN (1-795): 0: 706: 100.00
+	Hs
		82493 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		B9A6K1_HUMAN (1-795): 0: 706: 100.00
+	Hs
		891366 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		RBGP1_HUMAN (4-665): 3.03e-84: 291: 12.05
+	Hs
		306365 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		RBGP1_HUMAN (4-665): 3.03e-84: 291: 12.05
+	Hs
		1328072 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		RBGP1_HUMAN (4-665): 3.03e-84: 291: 12.05
+	Hs
		891232 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		TBC15_HUMAN (4-489): 4.78e-78: 267: 13.55
+	Hs
		891183 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		TBC9B_HUMAN (6-580): 8.99e-74: 263: 14.09
+	Hs
		306240 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		TBC15_HUMAN (4-489): 4.78e-78: 267: 13.55
+	Hs
		1253208 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TBC15_HUMAN (4-489): 4.78e-78: 267: 13.55
+	Hs
		1146079 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TBC9B_HUMAN (6-580): 8.99e-74: 263: 14.09
+	Hs
		1252977 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TBC16_HUMAN (14-487): 1.49e-72: 254: 16.25
+	Sc
		746044 ATG8_YEAST (1-116): 1.06e-58: 178: 56.03		GYP1_YEAST (22-367): 5.4e-70: 244: 14.76
+	Hs
		1328034 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TBC17_HUMAN (56-472): 1.31e-72: 251: 17.78
+	Dm
		1364630 Q9VEG5_DROME (1-116): 4.49e-54: 166: 51.72		Q9VPL5_DROME (6-477): 3.74e-71: 249: 14.79
+	Hs
		1315253 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TB10A_HUMAN (3-594): 5.29e-70: 241: 16.56
+	Hs
		891174 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		TBC25_HUMAN (57-363): 4.55e-51: 192: 16.51
+	Hs
		306201 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		TBC25_HUMAN (57-363): 4.55e-51: 192: 16.51
+	Hs
		1109690 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		TBC25_HUMAN (57-363): 4.55e-51: 192: 16.51
+	Hs
		1109691 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		TBC25_HUMAN (57-363): 4.55e-51: 192: 16.51