HitPredict

Interactor 1: MYL6 (P60660)
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
Gene: MYL6

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 151 Hs			1 191
+	Hs
		521681 MYL4_HUMAN (3-151): 7.24e-58: 180: 77.48		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		538657 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		891506 MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		538654 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		538658 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		483918 CALM1_HUMAN (5-77): 1.13e-11: 60.6: 28.77		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		483991 CALM2_HUMAN (5-77): 1.13e-11: 60.6: 28.77		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		484102 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		483915 CALM1_HUMAN (5-77): 1.13e-11: 60.6: 28.77		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		483989 CALM2_HUMAN (5-77): 1.13e-11: 60.6: 28.77		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		484093 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		648485 CALL3_HUMAN (5-77): 1.25e-10: 57.9: 26.03		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32