Protein: NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase (EC 2.1.1.202) (Multisite-specific tRNA:m5C-methyltransferase) (tRNA (cytosine-5-)-methyltransferase NCL1) (tRNA methyltransferase 4)

Gene: NCL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P38205

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002127 - tRNA wobble base cytosine methylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

523727

HSP71
Heat shock protein SSA1

2

9

High-throughput

0.584

High

795980

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

544619

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.552

High

383119

RLA4
Large ribosomal subunit protein P2B

2

1

High-throughput

0.537

High

795987

BRE5
UBP3-associated protein BRE5

1

4

High-throughput

0.536

High

795990

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.536

High

585262

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.515

High

795997

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.515

High

364488

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.501

High

585916

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.501

High

602422

PHO85
Cyclin-dependent protein kinase PHO85

1

3

High-throughput

0.501

High

642372

MCK1
Protein kinase MCK1

1

1

High-throughput

0.501

High

645918

DBF2
Cell cycle protein kinase DBF2

1

3

High-throughput

0.501

High

656440

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.501

High

656753

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

704678

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.501

High

795972

KSP1
Serine/threonine-protein kinase KSP1

1

3

High-throughput

0.501

High

795989

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

3

High-throughput

0.501

High

795992

VHS1
Serine/threonine-protein kinase VHS1

1

3

High-throughput

0.501

High

796000

SKM1
Serine/threonine-protein kinase SKM1

1

2

High-throughput

0.501

High

795974

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

560686

KIN2
Serine/threonine-protein kinase KIN2

1

0

High-throughput

0.480

High

574670

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.480

High

646380

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.480

High

758290

HSL1
Probable serine/threonine-protein kinase HSL1

1

0

High-throughput

0.480

High

795971

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.480

High

795977

PRK1
Actin-regulating kinase PRK1

1

0

Small-scale

0.480

High

795986

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

149722

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

392621

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

441868

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

512402

RS6A
Small ribosomal subunit protein eS6A

1

4

High-throughput

0.479

High

514603

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

670611

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

674579

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

689412

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

706901

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

734946

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

778286

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

792006

GBLP
Small ribosomal subunit protein RACK1

1

6

High-throughput

0.479

High

795973

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

795981

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

795988

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

4

High-throughput

0.479

High

795991

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

795999

DBP10
ATP-dependent RNA helicase DBP10

1

9

High-throughput

0.479

High

594338

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

736377

MET4
Transcriptional activator of sulfur metabolism MET4

1

0

High-throughput

0.458

High

795995

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

795998

PRR2
Serine/threonine-protein kinase PRR2

1

1

High-throughput

0.457

High

394486

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

403484

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.445

High

427245

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.445

High

435041

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.445

High

435552

RS9B
Small ribosomal subunit protein uS4B

1

3

High-throughput

0.445

High

526506

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

531710

RL4A
Large ribosomal subunit protein uL4A

1

4

High-throughput

0.445

High

569986

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.445

High

675940

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

684698

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.445

High

689014

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.445

High

795976

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

795979

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.445

High

795982

RL4B
Large ribosomal subunit protein uL4B

1

4

High-throughput

0.445

High

795984

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.445

High

795985

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.445

High

795993

RRP5
rRNA biogenesis protein RRP5

1

4

High-throughput

0.445

High

795983

YG51
Uncharacterized protein YGR237C

1

0

High-throughput

0.438

High

410086

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

433600

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.437

High

503003

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

512967

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

747321

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

753328

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

795994

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

154159

RL36B
Large ribosomal subunit protein eL36B

1

3

High-throughput

0.407

High

795975

TCPD
T-complex protein 1 subunit delta

1

2

High-throughput

0.407

High

482007

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

0

High-throughput

0.307

High

783978

RM10
Large ribosomal subunit protein uL15m

2

0

High-throughput

0.307

High

795978

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.269

Low

795996

YP150
Putative serine/threonine-protein kinase YPL150W

1

0

High-throughput

0.261

Low

691606

AP2B
AP-2 complex subunit beta

1

0

High-throughput

0.249

Low

503483

RS28B
Small ribosomal subunit protein eS28B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025