HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: REG3A (Q06141)
Regenerating islet-derived protein 3-alpha (REG-3-alpha) (Hepatointestinal pancreatic protein) (HIP/PAP) (Human proislet peptide) (HIP) (Pancreatitis-associated protein 1) (Regenerating islet-derived protein III-alpha) (Reg III-alpha) [Cleaved into: Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein 3-alpha 15 kDa form]
Gene: REG3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Lectin_C
Common GO terms	GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 175
+	Hs
		986135 ACTBL_HUMAN (2-375): 0: 735: 91.71		REG3A_HUMAN (1-175): 1.08e-45: 149: 100.00
+	Hs
		1122458 ACTBL_HUMAN (2-375): 0: 735: 91.71		CLC4D_HUMAN (20-174): 7.13e-39: 133: 21.02
+	Hs
		932117 ACTC_HUMAN (2-375): 0: 592: 94.12		REG3A_HUMAN (1-175): 1.08e-45: 149: 100.00
+	Hs
		915368 ACTA_HUMAN (2-375): 0: 591: 94.12		REG3A_HUMAN (1-175): 1.08e-45: 149: 100.00
+	Hs
		891847 ACTB_HUMAN (1-375): 0: 603: 100.00		CLC4G_HUMAN (28-174): 3.45e-34: 123: 18.24
+	Hs
		932451 ACTC_HUMAN (2-375): 0: 592: 94.12		CLC4E_HUMAN (25-173): 1.03e-33: 120: 17.65