HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: DIXC1 (Q155Q3)
Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)
Gene: DIXDC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 683
+	Hs
		725637 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN2_HUMAN (13-578): 1.19e-136: 425: 16.07
+	Hs
		211548 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN4_HUMAN (16-599): 1.42e-125: 396: 14.63
+	Hs
		211560 ACTC_HUMAN (2-375): 0: 592: 94.12		ACTN4_HUMAN (16-599): 1.42e-125: 396: 14.63
+	Hs
		211561 ACTS_HUMAN (2-375): 0: 592: 93.58		ACTN4_HUMAN (16-599): 1.42e-125: 396: 14.63
+	Hs
		164588 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTN2_HUMAN (9-577): 1.8e-100: 340: 18.23
+	Hs
		891697 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB2_HUMAN (9-577): 3.82e-97: 330: 17.21
+	Hs
		929824 ACTG_HUMAN (1-375): 0: 601: 98.93		SPTB2_HUMAN (9-577): 3.82e-97: 330: 17.21
+	Hs
		506816 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB1_HUMAN (9-537): 4.23e-95: 324: 17.79
+	Hs
		932107 ACTC_HUMAN (2-375): 0: 592: 94.12		SPTB2_HUMAN (9-577): 3.82e-97: 330: 17.21
+	Hs
		809100 ACTC_HUMAN (2-375): 0: 592: 94.12		UTRN_HUMAN (7-450): 9.06e-94: 321: 19.88
+	Oc
		933099 ACTS_RABIT (2-375): 0: 592: 93.58		Q07931_RABIT (13-238): 2.09e-66: 222: 19.91
+	Hs
		598031 ACTB_HUMAN (1-375): 0: 603: 100.00		FLNA_HUMAN (12-167): 8.68e-46: 178: 24.71
+	Hs
		598053 ACTG_HUMAN (1-375): 0: 601: 98.93		FLNA_HUMAN (12-167): 8.68e-46: 178: 24.71
+	Mm
		892189 ACTB_MOUSE (1-375): 0: 603: 100.00		FLNB_MOUSE (12-167): 7.52e-45: 175: 24.71
+	Hs
		891706 ACTB_HUMAN (1-375): 0: 603: 100.00		DYST_HUMAN (6-142): 3.04e-44: 174: 24.82
+	Hs
		891763 ACTB_HUMAN (1-375): 0: 603: 100.00		FLNC_HUMAN (12-167): 1.56e-44: 174: 25.29
+	Hs
		598055 ACTC_HUMAN (2-375): 0: 592: 94.12		FLNA_HUMAN (12-167): 8.68e-46: 178: 24.71
+	Hs
		261242 ACTC_HUMAN (2-375): 0: 592: 94.12		FLNB_HUMAN (12-167): 1.24e-44: 174: 24.71
+	Hs
		932113 ACTC_HUMAN (2-375): 0: 592: 94.12		DYST_HUMAN (6-142): 3.04e-44: 174: 24.82
+	Hs
		261239 ACTA_HUMAN (2-375): 0: 591: 94.12		FLNB_HUMAN (12-167): 1.24e-44: 174: 24.71