Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 20876399
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
and 6 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 375
Hs

1 2527
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024