HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: NFRKB (Q6P4R8)
Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B) (INO80 complex subunit G)
Gene: NFRKB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0045893 - positive regulation of DNA-templated transcription GO:0051726 - regulation of cell cycle
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1299
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 735: 91.71		MUC1_HUMAN (696-1293): 8.45e-32: 137: 12.31
+	Hs
		1122431 ACTBL_HUMAN (2-375): 0: 735: 91.71		SRCAP_HUMAN (558-1298): 6.1e-22: 105: 10.72
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 591: 94.12		MUC1_HUMAN (696-1293): 8.45e-32: 137: 12.31
+	Hs
		891853 ACTB_HUMAN (1-375): 0: 603: 100.00		SRCAP_HUMAN (558-1298): 6.1e-22: 105: 10.72
+	Hs
		929905 ACTG_HUMAN (1-375): 0: 601: 98.93		SRCAP_HUMAN (558-1298): 6.1e-22: 105: 10.72
+	Hs
		932219 ACTC_HUMAN (2-375): 0: 592: 94.12		SRCAP_HUMAN (558-1298): 6.1e-22: 105: 10.72
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 592: 94.12		SYNJ1_HUMAN (928-1292): 3.39e-13: 76.9: 10.88
+	Hs
		932156 ACTC_HUMAN (2-375): 0: 592: 94.12		MDC1_HUMAN (819-1297): 1.15e-11: 71.8: 12.32