Interactor 1: TAF6 (P49848)
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)
Gene: TAF6

Interactor 2: TAF8 (Q7Z7C8)
Transcription initiation factor TFIID subunit 8 (Protein taube nuss) (TBP-associated factor 43 kDa) (TBP-associated factor 8) (Transcription initiation factor TFIID 43 kDa subunit) (TAFII-43) (TAFII43) (hTAFII43)
Gene: TAF8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 31839598, 17375202, 14580349, 23292512, unassigned3799
Identification Methods affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains TAF6_C~TAF8_C
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0006367 - transcription initiation at RNA polymerase II promoter
GO:0016251 - RNA polymerase II general transcription initiation factor activity
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 677
Hs

1 310
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025