Protein: IFNG
Interferon gamma (IFN-gamma) (Immune interferon)

Gene: IFNG
Organism: Homo sapiens
Interactions: 34
UniProt ID: P01579

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001774 - microglial cell activation
GO:0001819 - positive regulation of cytokine production
GO:0002250 - adaptive immune response
GO:0002281 - macrophage activation involved in immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352913

INGR1
Interferon gamma receptor 1

7

1

Small-scale

0.970

High

352917

INGR2
Interferon gamma receptor 2

1

1

Small-scale

0.724

High

352915

CREB1
Cyclic AMP-responsive element-binding protein 1

2

2

Small-scale

0.618

High

352910

JUN
Transcription factor Jun

2

5

Small-scale

0.601

High

352929

STAT4
Signal transducer and activator of transcription 4

2

3

Small-scale

0.584

High

352907

IFNG
Interferon gamma

1

0

Small-scale

0.546

High

352924

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.536

High

352925

ACTA
Actin, aortic smooth muscle

1

1

High-throughput

0.536

High

352914

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

4

Small-scale

0.534

High

135005

TRI38
E3 ubiquitin-protein ligase TRIM38

1

0

High-throughput

0.513

High

352908

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.513

High

352909

ICAM1
Intercellular adhesion molecule 1

1

0

High-throughput

0.513

High

352921

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.513

High

352935

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.513

High

352911

IRF1
Interferon regulatory factor 1

1

0

Small-scale

0.512

High

352920

STAT6
Signal transducer and activator of transcription 6

1

3

Small-scale

0.501

High

352932

LMO7
LIM domain only protein 7

1

1

High-throughput

0.489

High

352938

LIMC1
LIM and calponin homology domains-containing protein 1

1

1

High-throughput

0.489

High

352918

STAT3
Signal transducer and activator of transcription 3

1

3

Small-scale

0.479

High

352919

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

3

Small-scale

0.479

High

352922

CTCF
Transcriptional repressor CTCF

1

1

Small-scale

0.479

High

352926

CREM
cAMP-responsive element modulator

1

2

Small-scale

0.479

High

352927

TF65
Transcription factor p65

1

2

Small-scale

0.479

High

352937

TBX21
T-box transcription factor TBX21

1

1

Small-scale

0.479

High

352912

I23O1
Indoleamine 2,3-dioxygenase 1

1

0

Small-scale

0.458

High

352928

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.458

High

352934

PROX1
Prospero homeobox protein 1

1

0

Small-scale

0.458

High

352916

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

3

Small-scale

0.437

High

352936

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

0

High-throughput

0.328

High

352923

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.279

Low

352930

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.279

Low

352933

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.279

Low

352931

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024