Protein: TAF3
Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140)

Gene: TAF3
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q5VWG9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001673 - male germ cell nucleus
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1091625

TAF10
Transcription initiation factor TFIID subunit 10

5

2

Small-scale

0.920

High

1161898

H31T
Histone H3.1t

3

20

Small-scale

0.849

High

639754

TAF1
Transcription initiation factor TFIID subunit 1

3

15

Small-scale

0.847

High

1149776

TAF5
Transcription initiation factor TFIID subunit 5

2

11

Small-scale

0.789

High

1016934

H33
Histone H3.3

2

20

Small-scale

0.785

High

998424

H31
Histone H3.1

2

20

Small-scale

0.768

High

674199

BRD2
Bromodomain-containing protein 2

2

20

High-throughput

0.754

High

1141166

BRD3
Bromodomain-containing protein 3

2

20

High-throughput

0.754

High

130766

TAF4
Transcription initiation factor TFIID subunit 4

1

11

High-throughput

0.691

High

1159294

TAF9
Transcription initiation factor TFIID subunit 9

1

2

High-throughput

0.691

High

1218901

TAF9B
Transcription initiation factor TFIID subunit 9B

1

2

High-throughput

0.691

High

628803

TBP
TATA-box-binding protein

4

4

Small-scale

0.689

High

1204706

TAF7L
Transcription initiation factor TFIID subunit 7-like

3

1

High-throughput

0.662

High

1149843

TAF7
Transcription initiation factor TFIID subunit 7

3

1

Small-scale

0.656

High

1218883

TAF8
Transcription initiation factor TFIID subunit 8

3

0

High-throughput

0.634

High

1157579

TAF12
Transcription initiation factor TFIID subunit 12

3

0

Small-scale

0.622

High

260072

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.618

High

502385

H2A1
Histone H2A type 1

1

12

High-throughput

0.618

High

883575

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

1218885

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.618

High

1218888

PHIP
PH-interacting protein

1

20

High-throughput

0.618

High

1218889

KAT6A
Histone acetyltransferase KAT6A

1

18

High-throughput

0.618

High

1218890

KAT2A
Histone acetyltransferase KAT2A

1

20

Small-scale

0.618

High

1218898

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

7

High-throughput

0.618

High

1149823

TAF11
Transcription initiation factor TFIID subunit 11

2

1

Small-scale

0.611

High

447103

NPM
Nucleophosmin

2

3

High-throughput

0.601

High

1149807

TAF13
Transcription initiation factor TFIID subunit 13

2

0

Small-scale

0.585

High

944678

KLF3
Krueppel-like factor 3

2

20

High-throughput

0.584

High

1153813

SMAD2
Mothers against decapentaplegic homolog 2

2

7

Small-scale

0.584

High

1218886

ZCH10
Zinc finger CCHC domain-containing protein 10

2

0

High-throughput

0.576

High

336000

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.536

High

848649

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.536

High

892038

TAF6
Transcription initiation factor TFIID subunit 6

1

1

High-throughput

0.536

High

1218881

TAF2
Transcription initiation factor TFIID subunit 2

1

1

High-throughput

0.536

High

1218887

MICA1
[F-actin]-monooxygenase MICAL1

1

12

High-throughput

0.536

High

481305

HMGB1
High mobility group protein B1

1

20

Small-scale

0.508

High

910939

IMA1
Importin subunit alpha-1

1

3

Small-scale

0.501

High

1134230

IMB1
Importin subunit beta-1

1

5

Small-scale

0.501

High

1218894

EFHD1
EF-hand domain-containing protein D1

1

1

High-throughput

0.489

High

143043

NFIB
Nuclear factor 1 B-type

1

18

High-throughput

0.479

High

154994

BHE40
Class E basic helix-loop-helix protein 40

1

2

Small-scale

0.479

High

190951

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

10

High-throughput

0.479

High

339774

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

400978

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.479

High

474048

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

487413

PARP1
Poly [ADP-ribose] polymerase 1

1

14

High-throughput

0.479

High

581668

MYOD1
Myoblast determination protein 1

1

6

High-throughput

0.479

High

675539

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.479

High

685224

PAX6
Paired box protein Pax-6

1

15

High-throughput

0.479

High

702978

DPOD1
DNA polymerase delta catalytic subunit

1

2

High-throughput

0.479

High

738992

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

833965

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

837053

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.479

High

851589

GATA4
Transcription factor GATA-4

1

9

Small-scale

0.479

High

862212

YAP1
Transcriptional coactivator YAP1

1

12

High-throughput

0.479

High

879181

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

14

High-throughput

0.479

High

886510

CTCF
Transcriptional repressor CTCF

1

6

Small-scale

0.479

High

888124

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

904828

MECP2
Methyl-CpG-binding protein 2

1

9

High-throughput

0.479

High

979810

H4
Histone H4

1

9

Small-scale

0.479

High

986482

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

6

High-throughput

0.479

High

1024627

VIGLN
Vigilin

1

11

High-throughput

0.479

High

1087792

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1133457

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1137346

SUZ12
Polycomb protein SUZ12

1

3

High-throughput

0.479

High

1152698

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1153968

SMAD1
Mothers against decapentaplegic homolog 1

1

7

Small-scale

0.479

High

1155457

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.479

High

1218880

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

3

High-throughput

0.479

High

1218882

TBPL2
TATA box-binding protein-like 2

1

4

Small-scale

0.479

High

1218884

SMC5
Structural maintenance of chromosomes protein 5

1

13

High-throughput

0.479

High

1218891

FEV
Protein FEV

1

17

High-throughput

0.479

High

1218892

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1218895

DDX23
Probable ATP-dependent RNA helicase DDX23

1

5

High-throughput

0.479

High

1218897

KLF16
Krueppel-like factor 16

1

16

High-throughput

0.479

High

1218899

SP130
Histone deacetylase complex subunit SAP130

1

11

Small-scale

0.479

High

1218902

AFF4
AF4/FMR2 family member 4

1

15

High-throughput

0.479

High

1218903

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.479

High

1218904

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

984806

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

1218896

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

687250

HMGB2
High mobility group protein B2

1

20

High-throughput

0.445

High

1218900

SNX25
Sorting nexin-25

1

2

High-throughput

0.437

High

1218893

SPT25
Spermatogenesis-associated protein 25

2

0

High-throughput

0.313

High

1065842

MZT1
Mitotic-spindle organizing protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025