Protein: TAF6
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)

Gene: TAF6
Organism: Homo sapiens
Interactions: 132
UniProt ID: P49848

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

892043

TAF8
Transcription initiation factor TFIID subunit 8

8

3

Small-scale

0.969

High

892034

TAF9
Transcription initiation factor TFIID subunit 9

7

8

Small-scale

0.967

High

892035

H31T
Histone H3.1t

3

5

Small-scale

0.814

High

892025

TAF5
Transcription initiation factor TFIID subunit 5

2

7

Small-scale

0.768

High

628728

TBP
TATA-box-binding protein

13

6

Small-scale

0.757

High

892067

TAF9B
Transcription initiation factor TFIID subunit 9B

1

8

Small-scale

0.747

High

892017

NFYC
Nuclear transcription factor Y subunit gamma

2

0

Small-scale

0.728

High

892014

TAF10
Transcription initiation factor TFIID subunit 10

5

5

Small-scale

0.702

High

892032

TAF12
Transcription initiation factor TFIID subunit 12

4

5

Small-scale

0.692

High

639686

TAF1
Transcription initiation factor TFIID subunit 1

4

14

Small-scale

0.680

High

892037

TAF7L
Transcription initiation factor TFIID subunit 7-like

3

3

High-throughput

0.662

High

418886

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.618

High

754764

H2B1B
Histone H2B type 1-B

1

2

High-throughput

0.618

High

892004

H31
Histone H3.1

1

5

High-throughput

0.618

High

892010

RBBP4
Histone-binding protein RBBP4

1

4

Small-scale

0.618

High

892033

RBBP7
Histone-binding protein RBBP7

1

4

Small-scale

0.618

High

892039

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.618

High

892049

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.618

High

892055

PHIP
PH-interacting protein

1

5

High-throughput

0.618

High

421731

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.602

High

892023

BRD3
Bromodomain-containing protein 3

2

14

High-throughput

0.601

High

413416

P53
Cellular tumor antigen p53

2

0

Small-scale

0.598

High

833900

HNF4A
Hepatocyte nuclear factor 4-alpha

2

4

Small-scale

0.595

High

892008

TF65
Transcription factor p65

2

1

Small-scale

0.595

High

259632

BRD4
Bromodomain-containing protein 4

2

13

High-throughput

0.584

High

648336

USF1
Upstream stimulatory factor 1

2

1

Small-scale

0.584

High

674109

BRD2
Bromodomain-containing protein 2

2

14

High-throughput

0.584

High

892000

H4
Histone H4

2

2

High-throughput

0.584

High

892020

NFIX
Nuclear factor 1 X-type

2

4

High-throughput

0.584

High

892047

BANP
Protein BANP

2

0

High-throughput

0.580

High

708881

T2EA
General transcription factor IIE subunit 1

2

0

Small-scale

0.577

High

892024

RNPS1
RNA-binding protein with serine-rich domain 1

2

0

High-throughput

0.576

High

892005

H33
Histone H3.3

1

5

Small-scale

0.575

High

395707

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

612940

EGR1
Early growth response protein 1

2

0

High-throughput

0.559

High

853935

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

892038

TAF3
Transcription initiation factor TFIID subunit 3

1

1

High-throughput

0.536

High

892048

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

3

High-throughput

0.536

High

892018

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

335968

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.513

High

629081

CCNA2
Cyclin-A2

1

0

High-throughput

0.513

High

691680

MK03
Mitogen-activated protein kinase 3

1

0

High-throughput

0.513

High

769679

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.513

High

848600

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

892056

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

0

High-throughput

0.513

High

659664

NFYA
Nuclear transcription factor Y subunit alpha

1

1

Small-scale

0.501

High

892021

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

4

Small-scale

0.501

High

130718

TAF4
Transcription initiation factor TFIID subunit 4

1

2

Small-scale

0.500

High

278275

NCOR1
Nuclear receptor corepressor 1

1

0

Small-scale

0.480

High

670068

NFYB
Nuclear transcription factor Y subunit beta

1

0

Small-scale

0.480

High

777258

AHR
Aryl hydrocarbon receptor

1

0

Small-scale

0.480

High

157101

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

339690

KLF8
Krueppel-like factor 8

1

4

High-throughput

0.479

High

411584

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

472241

MYL3
Myosin light chain 3

1

1

High-throughput

0.479

High

577416

ETS1
Protein C-ets-1

1

5

High-throughput

0.479

High

581631

MYOD1
Myoblast determination protein 1

1

1

High-throughput

0.479

High

659186

SP100
Nuclear autoantigen Sp-100

1

2

High-throughput

0.479

High

685128

PAX6
Paired box protein Pax-6

1

1

High-throughput

0.479

High

694933

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

738958

ELF1
ETS-related transcription factor Elf-1

1

5

High-throughput

0.479

High

776036

SOX5
Transcription factor SOX-5

1

1

Small-scale

0.479

High

837026

ELK3
ETS domain-containing protein Elk-3

1

5

High-throughput

0.479

High

878781

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

891995

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

3

Small-scale

0.479

High

891999

TBPL1
TATA box-binding protein-like 1

1

6

High-throughput

0.479

High

892006

HEN1
Helix-loop-helix protein 1

1

1

High-throughput

0.479

High

892011

EP300
Histone acetyltransferase p300

1

8

High-throughput

0.479

High

892013

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

Small-scale

0.479

High

892015

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.479

High

892016

HDAC1
Histone deacetylase 1

1

2

Small-scale

0.479

High

892019

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

2

High-throughput

0.479

High

892022

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.479

High

892026

TAF13
Transcription initiation factor TFIID subunit 13

1

5

High-throughput

0.479

High

892027

TAF11
Transcription initiation factor TFIID subunit 11

1

4

Small-scale

0.479

High

892028

TAF7
Transcription initiation factor TFIID subunit 7

1

3

Small-scale

0.479

High

892029

ELF2
ETS-related transcription factor Elf-2

1

4

High-throughput

0.479

High

892030

SMAD2
Mothers against decapentaplegic homolog 2

1

1

Small-scale

0.479

High

892031

SMAD1
Mothers against decapentaplegic homolog 1

1

1

Small-scale

0.479

High

892036

BRDT
Bromodomain testis-specific protein

1

15

High-throughput

0.479

High

892044

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

4

Small-scale

0.479

High

892046

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

892051

SMRC2
SWI/SNF complex subunit SMARCC2

1

2

Small-scale

0.479

High

892057

HDAC2
Histone deacetylase 2

1

2

Small-scale

0.479

High

892058

KAT2A
Histone acetyltransferase KAT2A

1

14

High-throughput

0.479

High

892059

SMRC1
SWI/SNF complex subunit SMARCC1

1

2

Small-scale

0.479

High

892063

FEV
Protein FEV

1

5

High-throughput

0.479

High

892064

ELF4
ETS-related transcription factor Elf-4

1

5

High-throughput

0.479

High

892066

KLF16
Krueppel-like factor 16

1

4

High-throughput

0.479

High

892068

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

892070

KLF15
Krueppel-like factor 15

1

4

High-throughput

0.479

High

892071

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.479

High

892072

TRRAP
Transformation/transcription domain-associated protein

1

4

Small-scale

0.479

High

892073

KLF12
Krueppel-like factor 12

1

4

High-throughput

0.479

High

194059

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

282226

SAP30
Histone deacetylase complex subunit SAP30

1

0

Small-scale

0.458

High

352090

MBD3
Methyl-CpG-binding domain protein 3

1

0

Small-scale

0.458

High

446774

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

464366

ERCC1
DNA excision repair protein ERCC-1

1

0

Small-scale

0.458

High

588209

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

675418

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

713954

PML
Protein PML

1

0

High-throughput

0.458

High

767703

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

861925

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

886637

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

891994

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

891997

TF2AA
Transcription initiation factor IIA subunit 1

1

0

High-throughput

0.458

High

892001

RAN
GTP-binding nuclear protein Ran

1

0

Small-scale

0.458

High

892002

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

892003

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

892007

KMT2A
Histone-lysine N-methyltransferase 2A

1

0

Small-scale

0.458

High

892009

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.458

High

892012

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

Small-scale

0.458

High

892042

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

892045

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

892053

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

Small-scale

0.458

High

892060

SH3K1
SH3 domain-containing kinase-binding protein 1

1

0

Small-scale

0.458

High

892062

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.458

High

892069

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

687161

HMGB2
High mobility group protein B2

1

3

High-throughput

0.445

High

892061

MOAP1
Modulator of apoptosis 1

1

1

High-throughput

0.445

High

892041

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

686032

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.426

High

891996

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.426

High

891998

WDR5
WD repeat-containing protein 5

1

0

Small-scale

0.426

High

892054

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

892052

ZCH10
Zinc finger CCHC domain-containing protein 10

2

0

High-throughput

0.313

High

892065

SPT25
Spermatogenesis-associated protein 25

2

0

High-throughput

0.313

High

892040

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.279

Low

62472

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

87376

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

892050

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025