HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: MPP7 (Q5T2T1)
MAGUK p55 subfamily member 7
Gene: MPP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 576
+	Hs
		925341 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		545425 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		1132891 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		951060 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		894107 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		159189 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33
+	Hs
		159149 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33
+	Hs
		159267 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33
+	Hs
		159192 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33
+	Hs
		159184 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33
+	Hs
		925239 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Mm
		925797 RAC1_MOUSE (1-192): 1.92e-84: 249: 92.71		DLG4_MOUSE (91-225): 1.04e-21: 101: 16.08
+	Hs
		545346 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		1021562 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		892341 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		950954 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Mm
		1111996 Q3TLP8_MOUSE (1-192): 6.25e-80: 238: 83.89		DLG4_MOUSE (91-225): 1.04e-21: 101: 16.08
+	Hs
		893948 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		892525 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		DLG3_HUMAN (139-485): 4.74e-17: 87: 10.74
+	Hs
		951207 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		DLG3_HUMAN (139-485): 4.74e-17: 87: 10.74