HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: MILK1 (Q8N3F8)
MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13)
Gene: MICALL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0030036 - actin cytoskeleton organization GO:0031941 - filamentous actin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 863
+	Hs
		925433 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00
+	Hs
		1232332 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00
+	Hs
		925443 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		545503 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		1242508 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		892491 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		297823 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		297812 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		297840 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		297819 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		925201 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		164599 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		545327 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		963416 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		892322 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		164665 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		164589 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		925387 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MICA3_HUMAN (8-107): 1.44e-22: 106: 54.00
+	Hs
		1186089 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		MICA3_HUMAN (8-107): 1.44e-22: 106: 54.00
+	Hs
		892450 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		MICA3_HUMAN (8-107): 1.44e-22: 106: 54.00