HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: EHD1 (Q9H4M9)
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)
Gene: EHD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 534
+	Hs
		545618 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		EHD1_HUMAN (1-534): 0: 822: 100.00
+	Hs
		1330916 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		EHD1_HUMAN (1-534): 0: 822: 100.00
+	Hs
		564685 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		EHD1_HUMAN (1-534): 0: 822: 100.00
+	Hs
		925602 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		EHD4_HUMAN (1-532): 0: 776: 74.95
+	Hs
		925677 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		545664 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		1328986 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		EHD4_HUMAN (1-532): 0: 776: 74.95
+	Hs
		1330957 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		892636 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		951410 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		894411 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		EHD4_HUMAN (1-532): 0: 776: 74.95
+	Hs
		894522 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		900984 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		436544 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		564712 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		894047 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		ITSN1_HUMAN (426-527): 3.14e-29: 125: 37.26