HitPredict

Interactor 1: SNP25 (P60880)
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)
Gene: SNAP25

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 11524423, 9030619, 11832227, 22890573, 20798282, 30610939
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, two hybrid, far western blotting, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005484 - SNAP receptor activity
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006887 - exocytosis
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 206
Hs

1 116
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024