Protein: IMDH2
Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205)

Gene: IMDH2, IMD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 101
UniProt ID: P38697

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003729 - mRNA binding
GO:0003938 - IMP dehydrogenase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

802100

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

4

14

High-throughput

0.896

High

802099

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

3

14

High-throughput

0.855

High

802102

BUD32
EKC/KEOPS complex subunit BUD32

2

2

Small-scale

0.625

High

448709

SNF1
Carbon catabolite-derepressing protein kinase

1

3

Small-scale

0.618

High

802080

IMDH1
Putative inosine-5'-monophosphate dehydrogenase 1

1

14

High-throughput

0.618

High

802109

GCN5
Histone acetyltransferase GCN5

2

5

High-throughput

0.549

High

671414

RNA14
mRNA 3'-end-processing protein RNA14

1

3

High-throughput

0.536

High

721907

XPO1
Exportin-1

1

1

High-throughput

0.536

High

737598

GSH1
Glutamate--cysteine ligase

1

1

High-throughput

0.536

High

751389

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.536

High

795760

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

4

High-throughput

0.536

High

802079

PCF11
Protein PCF11

1

1

High-throughput

0.536

High

802082

IF2P
Eukaryotic translation initiation factor 5B

1

5

High-throughput

0.536

High

802114

MAG2
E3 ubiquitin-protein ligase MAG2

1

2

High-throughput

0.536

High

802108

IMA1
Importin subunit alpha

1

0

High-throughput

0.518

High

364504

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.501

High

574675

KSS1
Mitogen-activated protein kinase KSS1

1

2

High-throughput

0.501

High

632664

DBP4
ATP-dependent RNA helicase HCA4

1

3

High-throughput

0.489

High

644659

MAG
DNA-3-methyladenine glycosylase

1

2

High-throughput

0.489

High

793471

MAK5
ATP-dependent RNA helicase MAK5

1

4

High-throughput

0.489

High

802078

SEC31
Protein transport protein SEC31

1

4

High-throughput

0.489

High

802091

KRI1
Protein KRI1

1

1

High-throughput

0.489

High

802104

NOP13
Nucleolar protein 13

1

2

High-throughput

0.489

High

802113

FAR8
Factor arrest protein 8

1

1

High-throughput

0.489

High

802117

CLP1
mRNA cleavage and polyadenylation factor CLP1

1

1

High-throughput

0.489

High

802094

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

149736

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

438681

SC160
Protein SCP160

1

4

High-throughput

0.479

High

514614

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

558701

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

594351

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

Small-scale

0.479

High

689020

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

739621

SPT16
FACT complex subunit SPT16

1

2

High-throughput

0.479

High

740907

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

5

High-throughput

0.479

High

778301

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

792019

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

797733

AIM4
Altered inheritance of mitochondria protein 4

1

2

High-throughput

0.479

High

802077

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

802088

TM108
Protein TMA108

1

3

High-throughput

0.479

High

802095

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.479

High

802098

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

802101

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.479

High

802103

GIS2
Zinc finger protein GIS2

1

4

High-throughput

0.479

High

802106

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

802107

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.479

High

802110

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

802116

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

802121

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

802122

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

802123

YRA1
RNA annealing protein YRA1

1

4

Small-scale

0.479

High

735827

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.470

High

802084

RSM18
Small ribosomal subunit protein bS18m

1

1

High-throughput

0.470

High

802111

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

523820

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

544730

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

617791

SNF6
Transcription regulatory protein SNF6

1

1

High-throughput

0.445

High

738094

MYO4
Myosin-4

1

2

High-throughput

0.445

High

739138

PRP19
Pre-mRNA-processing factor 19

1

5

Small-scale

0.445

High

739354

ZUO1
Zuotin

1

4

High-throughput

0.445

High

779180

NDK
Nucleoside diphosphate kinase

1

2

High-throughput

0.445

High

794113

FAT2
Oxalate--CoA ligase

1

3

High-throughput

0.445

High

802085

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

802086

ATAD2
ATPase histone chaperone YTA7

1

1

High-throughput

0.445

High

802097

TAF1
Transcription initiation factor TFIID subunit 1

1

1

High-throughput

0.445

High

802118

HRK1
Serine/threonine-protein kinase HRK1

1

2

High-throughput

0.445

High

802124

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

2

High-throughput

0.445

High

383676

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

410104

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

433615

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

455035

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

503016

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504186

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

512415

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

512982

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

654716

SPA2
Protein SPA2

1

2

Small-scale

0.437

High

677374

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

689427

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

706991

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

747336

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.437

High

753344

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

798681

YB8A
Putative uncharacterized protein YBR285W

1

2

Small-scale

0.437

High

802090

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.437

High

802092

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.437

High

802112

DHR1
Probable ATP-dependent RNA helicase DHR1

1

3

High-throughput

0.437

High

802115

URN1
Pre-mRNA-splicing factor URN1

1

2

High-throughput

0.437

High

802119

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

802120

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

700063

FUN19
SWIRM domain-containing protein FUN19

1

0

High-throughput

0.426

High

757482

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.426

High

802081

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.426

High

802089

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.426

High

802105

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.426

High

382077

H4
Histone H4

1

3

High-throughput

0.407

High

793821

DPOA2
DNA polymerase alpha subunit B

1

1

High-throughput

0.407

High

802087

PSF2
DNA replication complex GINS protein PSF2

1

2

High-throughput

0.407

High

802093

NSE4
Non-structural maintenance of chromosome element 4

2

0

High-throughput

0.295

High

449409

SPT2
Protein SPT2

1

0

High-throughput

0.279

Low

150070

COQ4
Ubiquinone biosynthesis protein COQ4, mitochondrial

1

0

High-throughput

0.232

Low

570803

ABF1
ARS-binding factor 1

1

0

High-throughput

0.232

Low

802083

NPR2
Nitrogen permease regulator 2

1

0

High-throughput

0.232

Low

802096

STU2
Protein STU2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025